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Clinical Trial Summary

EPOgen and Restrictive Transfusions in Patients Undergoing Cardiac Surgery (EPORT)


Clinical Trial Description

The investigator proposes a study investigating the use of restrictive transfusion triggers and administration of single preoperative high dose shot of epoetin alfa (rhEPO) in a young (age < 65 years of age) population undergoing cardiac surgery. The investigator believes that participants can tolerate a lower Hemoglobin (Hgb). Therefore, the control group will benefit from a restrictive transfusion trigger and experimental group will benefit from EPO providing a synergistic stimulus for erythropoiesis. This proposed study has potential to reduce overall transfusion utilization in cardiac surgery and improve standard of care. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02802592
Study type Interventional
Source Johns Hopkins University
Contact
Status Terminated
Phase Phase 1/Phase 2
Start date May 2015
Completion date February 27, 2017

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