Clinical Trials Logo
  1. Home
  2. Cardiac Transplantation
  3. NCT01017029

Everolimus in de Novo Heart Transplant Recipients — EVERHEART  

Cardiac Transplantation Clinical Trial

Official title:
Early vs. Delayed EVERolimus in de Novo HEART Transplant Recipients: Optimization of the Safety/Efficacy Profile (EVERHEART Study)

Clinical Trial Summary

The purpose of this study, in de novo heart transplant patients, is to evaluate whether delayed introduction of everolimus reduces the occurrence of wound healing problems, pericardial and/or pleural effusion and early acute renal insufficiency, as compared with immediate introduction of everolimus, in the firs six months after heart transplantation.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01017029
Study type Interventional
Source Novartis
Contact
Status Completed
Phase Phase 4
Start date September 2009
Completion date December 2013
View Details
See also
  Status Clinical Trial Phase
Completed NCT02672683 - Non Invasive Detection of Cardiac Allograft Rejection by Circulating microRNAs
Terminated NCT00338455 - Natrecor (Nesiritide) in Transplant-Eligible Management of Congestive Heart Failure-TMAC Phase 2
Completed NCT00170794 - Renal Safety of Everolimus in Addition to Cyclosporine Microemulsion in Cardiac Transplant Recipients. Phase 3
Completed NCT00000412 - Osteoporosis Prevention After Heart Transplant Phase 3
Completed NCT00716573 - Efficacy Study of Everolimus on Renal Function in Heart Transplant Recipients With Established Chronic Renal Failure Phase 4
Completed NCT02255123 - Retrospective Multicenter Study to Determine 4-Year Clinical Outcomes in Subjects Previously Enrolled in the CTOT-05 Study N/A
Active, not recruiting NCT00799188 - CERTICOEUR: A Secondary Prevention Study of Skin Cancers in Heart Transplant Patients. Everolimus Versus Calcineurin Inhibitors Multicenter Trial Phase 3
Terminated NCT00284531 - Use of Daclizumab for the Prevention of Allograft Rejection in Pediatric Heart Transplant Patients Phase 1/Phase 2
Active, not recruiting NCT05904678 - Anatomical and Functional Assessment of Ex-vivo Coronary Perfusion
Terminated NCT01235910 - Clinical Pharmacology of Aliskiren in Combination With Cyclosporine in Cardiac Transplantation Phase 4
Active, not recruiting NCT00581321 - Oral Water Ingestion in Heart Transplant Patients N/A
Terminated NCT00166153 - Outcomes in Pediatric Heart Transplant Recipients Receiving Cellcept N/A
Completed NCT00414895 - Absolute Myocardial Perfusion Measurement in the Transplanted Heart N/A
Completed NCT03145441 - Intraoperative Use of Extracorporeal Cytokine Adsorption During Orthotopic Heart Transplantation N/A