Cytokine Profiling Post-Heart Transplant

Cardiac Transplant Clinical Trial

Official title:

Cytokine Profiling of Cardiac Transplant Recipients

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT01643564
• Other study ID #: 1111M06547
• Status: Terminated
• Start date: November 2011
• Est. completion date: June 2012

Study information

• Verified date: October 2023
• Source: University of Minnesota
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Measurement of cytokine levels in post-cardiac transplant patients with unexplained graft dysfunction.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 34
• Est. completion date: June 2012
• Est. primary completion date: June 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

Group 1

• 18 years and older

• Cardiac Transplant recipient with graft dysfunction of unknown etiology

Group 2

• 18 years or older

• No history of heart failure or cardiac transplantation Group 3

• 18 years or older

• Class II-IV heart failure Group 4

• 18 years or older

• Heart Transplant 6 months or greater prior to blood draw

• No graft dysfunction

Exclusion Criteria:

Group 1 Heart Transplant with Unexplained Graft Dysfunction

• Cellular or antibody-mediated cardiac allograft dysfunction

Group 2 Normal Control group

• Active infection within 1 month of blood draw

• Known Inflammatory Disease

Group 3 Heart Failure Group

• Active infection within 1 month of blood draw

• Known Inflammatory Disease

Group 4 Heart Transplant with Normal Graft Function Group

• Active infection within 1 month of blood draw

• Known graft dysfunction

• Known Inflammatory Disease

Related Conditions & MeSH terms

• Cardiac Transplant

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University of Minnesota

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Differences in cytokine profiles between stable heart transplant recipients and those with acute rejection	Differences in cytokine profiles between stable heart transplant recipients and those with acute rejection	12 months