Cardiac Surgical Procedures Clinical Trial
— NGAL-CKFOfficial title:
Plasmatic Level of Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Predictive Marker of Acute Kidney Failure in Patients With Preoperative Chronic Kidney Failure Undergoing Cardiac Surgery.
Primary endpoint: To evaluate predictive value of plasmatic levels of Neutrophil Gelatinase Associated Lipocalin (NGAL) to reveal acute kidney failure after cardiac surgery in patients with preoperative chronic kidney failure Secondary endpoint is to obtain threshold values of NGAL.
| Status | Recruiting |
| Enrollment | 100 |
| Est. completion date | September 2013 |
| Est. primary completion date | July 2013 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 18 Years and older |
| Eligibility |
Inclusion Criteria: - Renal clearance less than 60 mL/min - Able to give written consent - Elective valve surgery - Elective CABG surgery Exclusion Criteria: - Less than 18 years old - Iodine injection within 3 days before surgery - Iodine injection within 24 first postoperative hours - preoperative infection - evolutive cancer disease - Refusal - Pregnancy - Unable to give written consent |
Observational Model: Case-Only, Time Perspective: Prospective
| Country | Name | City | State |
|---|---|---|---|
| France | Centre hospitalier Universitaire (CHU) Jean Minjoz | Besançon | Franche-Comté |
| Lead Sponsor | Collaborator |
|---|---|
| Hopital Jean Minjoz |
France,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Neutrophil Gelatinase Associated Lipocalin (NGAL) level | From surgery to discharge from hospital | No |
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|---|---|---|---|
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