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Clinical Trial Summary

We used the preoperative intervention of iron sucrose in combination with human erythropoietin and vitamin C as an innovative combination therapy. This combined treatment strategy aims to improve perioperative anaemia in patients by promoting erythropoiesis and improving iron metabolism. Compared with previous perioperative intravenous iron supplementation, this innovative combination therapy strategy takes into account multiple aspects of iron metabolism as well as the biological mechanisms of erythropoiesis, providing a more comprehensive intervention. Management of perioperative anaemia in previous studies has largely relied on single intravenous iron supplementation therapy, and although this approach has been effective in raising iron levels, its effectiveness may be limited in patients who have impaired iron utilisation or in situations where concurrent stimulation of erythropoiesis is required. The use of iron sucrose in combination with human erythropoietin and vitamin C, on the other hand, is based on an integrative therapeutic concept aimed at providing a more comprehensive response to perioperative anaemia by simultaneously promoting effective iron utilisation and erythropoiesis.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05353348
Study type Interventional
Source Second Affiliated Hospital, School of Medicine, Zhejiang University
Contact Min Yan
Phone 13757118632
Email zryanmin@zju.edu.cn
Status Recruiting
Phase N/A
Start date March 15, 2023
Completion date December 31, 2024

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