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Evaluate the Protective Effect of Conditioning With Sevoflurane on the Myocardium — SUPRA  

Cardiac Surgery Clinical Trial

Official title:
Evaluate the Protective Effect of Conditioning With Sevoflurane Versus Propofol on the Myocardium in Scheduled Aortic Valve Replacement Surgery

Clinical Trial Summary

Heart surgery is a considerable source of stress for the myocardium that must be minimized.

Troponin Ic is a reliable marker to determine the level of this myocardial stress.

Studies have shown that post-conditioning with AVH has a protective effect on the myocardium, if the treatment is initiated at the start of the ischemia.

The aim of this study is to evaluate the protective effect on the myocardium (by measuring troponin levels) of the association of pre-conditioning and post-conditioning with Sevoflurane (AVH) sedation administered during and after scheduled surgery for valve replacement, via sternotomy or thoracotomy compared with total intravenous anaesthesia with Propofol.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02851433
Study type Interventional
Source Centre Hospitalier Universitaire Dijon
Contact
Status Completed
Phase Phase 4
Start date October 14, 2015
Completion date September 4, 2017
View Details
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