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Cardiac Surgery Patients clinical trials

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NCT ID: NCT06437886 Enrolling by invitation - Clinical trials for Cardiac Surgery Patients

High-dose Opioid Versus Opioid-sparing Anaesthesia in Cardiac Surgery

Start date: April 22, 2024
Phase: N/A
Study type: Interventional

BACKGROUND In cardiac surgery, high-dose opioids contributes to adverse events associated with poor postoperative outcomes. There is growing evidence that nerve block-based opioid-sparing protocols may reduce perioperative opioid consumption with equally analgesia management and consequently improve patient's postoperative recovery. OBJECTIVE To determine whether opioid-sparing anaesthesia based on pecto-intercostal fascial block and rectus sheath block (PIFB and RSB) could improve early postoperative recovery after cardiac surgery. DESIGN A randomised controlled trial. SETTING A tertiary hospital. PATIENTS Eighty 45-70 years old patients undergoing cardiac surgery were enrolled. Key exclusion criteria included extubation failure within 24 hours postoperatively, contraindication to interventions or drugs and a history of chronic pain or chronic opioid use. INTERVENTIONS Eligible patients were randomised at a 1 : 1 ratio to receive either PIFB and RSB-based opioid-sapring anaesthesia (intervention group) or opioid-based anaesthesia (control group). MAIN OUTCOME MEASURES The primary outcome was the global score of the 15-item Quality of Recovery (QoR-15) questionnaire at 24 h after surgery. Secondary outcomes included recovery-related time, postoperative pain score and rescue analgesia, health-related quality of life, the incidence of postoperative adeverse events and chronic pain.

NCT ID: NCT06402903 Completed - Clinical trials for Cardiac Surgery Patients

Physiotherapy in Patients in a Cardiac Intensive Care Unit

Start date: May 6, 2024
Phase:
Study type: Observational [Patient Registry]

Background. Cardiovascular diseases are a major cause of morbidity and mortality. The management of these patients requires multidisciplinary therapeutic approaches. Physiotherapy plays a fundamental role in the postoperative management of patients undergoing cardiac surgery. Objective: To analyse the relationship between the administration of a physiotherapy intervention and the time spent in the cardiac ICU and on the ward. Method. Retrospective cohort study. The medical records of 110 patients undergoing cardiac surgery who received a Physiotherapy intervention during their stay in the Intensive Care Unit will be analysed. Data will be collected from patients admitted to the cardiac ICU in 2023. The variables assessed will be: length of stay in ICU and hospital admission (days), age (years completed), weight (kg) and sex. A one-factor analysis of variance will be performed to calculate the association between the variables and a linear regression analysis will be used to describe the hospital stay variables as a function of the other predictor variables. Expected outcomes. Physiotherapy treatment in an Intensive Care Unit improves ICU and hospital stay times in patients undergoing cardiac surgery.

NCT ID: NCT06137547 Recruiting - Clinical trials for Cardiac Surgery Patients

HPI for Prevention of Hypotension During Cardiac Surgery

Start date: November 20, 2023
Phase: N/A
Study type: Interventional

Hypotension prediction index (HPI) was applied in various types of non-cardiac surgery with convincing benefits of preventing hypotensive events and clinical sequelae. Although HPI was validated in cardiac surgery, its clinical benefits are not proven yet. We aim to evaluate its effects on intraoperative hypotension and postoperative adverse events in cardiac surgery. In this randomized, single-blind trial, we will enroll adults scheduled for elective primary cardiac surgery under general anesthesia. Participants will be randomly assigned to intraoperative HPI-guided or non-HPI-guided hemodynamic management. The primary endpoint is the time-weighted average intraoperative hypotension below a mean arterial pressure threshold of 65 mmHg. The secondary endpoints are postoperative complications.

NCT ID: NCT04180852 Completed - Elderly Patients Clinical Trials

Investigating Nutrition and Functional Outcome in Critically Ill Patients

INFO
Start date: January 4, 2019
Phase:
Study type: Observational

This is a single-center, multi-ICU prospective observational trial evaluating current nutritional practice and its influence of the physical function of critically ill patients.

NCT ID: NCT03517605 Enrolling by invitation - Clinical trials for Cardiac Surgery Patients

Influence of a Rehabilitation Nursing Care Program on Quality of Life of Patients Undergoing Cardiac Surgery

Start date: December 10, 2017
Phase: N/A
Study type: Interventional

Cardiac rehabilitation is fundamental in the treatment of patients undergoing cardiac surgery regarding the educational, physical exercise and quality of life dimensions. Considering the competences of Specialist Nurses in Rehabilitation Nursing and the current prevalence of risk factors associated with cardiovascular disease, it is essential to implement programs in this area. This study aims to assess the impact of Specialist Nurses in Rehabilitation Nursing interventions on a cardiac rehabilitation program during hospitalization (phase I) and 1 month after cardiac surgery (phase II), in around 30 patients of both sexes, between 25 and 64 years old, and according to the American Heart Association and the American Association of Cardiovascular and Pulmonary Rehabilitation, met the criteria for low or moderate risk, class B for participation and exercise supervision, absence of signs/symptoms after cardiac surgery, with a left ventricular ejection fraction greater than 40%. Supervised interventions were performed during hospitalization, pre- and post-cardiac surgery, and 1 month after hospital discharge. In phase II, a physical exercise program was fulfilled according to the norms of the American College of Sports Medicine, comprising 3 sessions of physical exercise per week lasting between 30 to 60 minutes, including heating, aerobic exercise, and recovery/stretching. Hemodynamic data (blood pressure, heart rate, peripheral oxygen saturation) and the Borg scale were recorded in the initial, intermediate and final periods of each session. The aerobic capacity was evaluated through the 6-Minute Walk Test and health-related quality of life using the Short Form Health Survey 36 (SF-36V2) questionnaire.

NCT ID: NCT02755909 Completed - Clinical trials for Cardiac Surgery Patients

The Effect of Pre-anesthetic Education on Cardiac Surgery Patients' Anxiety Level

Start date: December 2015
Phase: N/A
Study type: Interventional

The study aims to investigate the effect of pre-anesthetic education on patients undergoing cardiac surgery

NCT ID: NCT02084030 Recruiting - Clinical trials for Cardiac Surgery Patients

Screening of Susceptibility Genes in Postoperative Cognitive Dysfunction(POCD)

Start date: March 2013
Phase: N/A
Study type: Observational

The aim of this study is to perform a whole-genome linkage analysis for identification of the susceptibility loci for POCD

NCT ID: NCT01231789 Recruiting - Clinical trials for Cardiac Surgery Patients

The Neuroprotection of Remote Ischemic Preconditioning (RIPC) on Cardiac Surgery in Multicenter

Start date: June 2009
Phase: N/A
Study type: Interventional

The current study is designed to clarify the neuroprotective effect of remote ischemic preconditioning on the patients underwent open-heart cardiac surgery.

NCT ID: NCT01048775 Completed - Clinical trials for Cardiac Surgery Patients

Bilateral Bispectral Index (BIS)-Monitoring in Cardiac Surgery Patients

Start date: February 2010
Phase: N/A
Study type: Observational

The bispectral index (BIS) is derived from a single-channel electroencephalogram (EEG) and provides information on the anaesthetic depth. Recently, a bilateral two-channel EEG-sensor has been introduced to monitor the BIS on both cerebral hemispheres. In some patients significant left-right differences may occur, whereas no relevant side differences are expected in the majority of patients. The aim of this study is to - investigate the incidence, duration and degree of left-right BIS differences - examine the relation between BIS differences and occurrence of cognitive deficits

NCT ID: NCT00444171 Completed - Blood Glucose Clinical Trials

Glucose Control by eMPC Algorithm in Peri- and Postoperative Period in Cardiac Surgery Patients

Start date: September 2006
Phase: N/A
Study type: Interventional

Randomized controlled trial to compare blood glucose control by the model predictive control algorithm with variable sampling rate (eMPC) with routine glucose management protocol (RMP) in peri- and postoperative period in cardiac surgery patients.