PET Imaging in Patients With Suspected Cardiac Sarcoidosis

Status Completed

Clinical Trial Summary

Gallium-68 DOTATATE is a radioactive tracer, a type of imaging drug that is labeled with a radioactive tag and injected into the body, which is approved by the U.S. Food and Drug Administration (FDA) to diagnose certain tumors. The study will see how the tracer is taken up in your heart before and after treatment using an imaging scan called Positron Emission Tomography / Computed Tomography (PET/CT). Investigators are doing this research study to find out if DOTATATE can help doctors diagnose people with cardiac (heart) sarcoidosis better as well as serve as a follow-up monitoring tool for a response to therapy.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03746847
Study type	Observational
Source	University of Pennsylvania
Contact
Status	Completed
Phase
Start date	December 1, 2018
Completion date	December 1, 2022

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04017936` - Interleukin-1 Blockade for Treatment of Cardiac Sarcoidosis	Phase 2
Recruiting	`NCT06131112` - Macrophage PET/CT Imaging Using 64Cu-DOTATATE for the Diagnosis of Cardiac Sarcoidosis
Terminated	`NCT03923049` - Feasibility and Accuracy of Hybrid Magnetic Resonance and Positron Emission Tomography With 18F-Fluorodeoxyglucose in Diagnosing Cardiac Sarcoidosis	N/A
Not yet recruiting	`NCT05954507` - Evaluation of the Prognostic Value of PET/MRI in Cardiac Sarcoidosis	N/A
Recruiting	`NCT04737317` - Diagnostic Criteria in Cardiac Sarcoidosis
Recruiting	`NCT03057002` - UTSW HP [13-C] Pyruvate Injection in HCM
Completed	`NCT03599414` - CASPA: CArdiac Sarcoidosis in PApworth
Withdrawn	`NCT02812849` - Somatostatin Receptor Imaging in Cardiac Sarcoidosis
Completed	`NCT01729169` - Cardiac Sarcoidosis: FDG PET vs. Ga-DOTANOC PET	N/A
Completed	`NCT03549598` - d68Ga-DOTATATE PET/CT Assessment of Cardiac Sarcoidosis	Phase 4
Recruiting	`NCT04758650` - Study of 68GaNOTA-Anti-MMR-VHH2 in Oncological Lesions, Cardiovascular Atherosclerosis, Syndrome With Abnormal Immune Activation and sarcoïdosis	Phase 2
Recruiting	`NCT04206163` - Somatostatin Receptor Imaging in Acute Myocarditis and Cardiac Sarcoidosis	N/A
Recruiting	`NCT05499637` - [68Ga]Ga-PentixaFor PET/CT in Acute Myocardial Inflammation	Phase 2
Recruiting	`NCT03593759` - Cardiac Sarcoidosis Randomized Trial	Phase 3
Recruiting	`NCT05145023` - Development and Validation of a Health-related Quality of Life Tool for Patients With Cardiac Sarcoidosis
Recruiting	`NCT03705884` - PET/MR Imaging In Patients With Cardiac Sarcoidosis	N/A
Enrolling by invitation	`NCT04774549` - Inflammatory Cardiomyopathy Bern Registry
Recruiting	`NCT03049254` - Mayo AVC Registry and Biobank
Recruiting	`NCT01477359` - Cardiac Sarcoidosis Multi-Center Prospective Cohort
Terminated	`NCT03103490` - 18F-FSPG PET/MRI or PET/CT Imaging of Cardiac Sarcoidosis or Inflammation	Phase 2