Hypotension Clinical Trial
Official title:
Study to Determine the Best Regimen for Administration of Phenylephrine During Spinal Anesthesia for Cesarean Delivery, as Determined by Maternal Blood Pressure and Cardiac Output
During Cesarean delivery, phenylephrine is used to maintain the patient's blood pressure.
Low blood pressure is the most common side effect of the spinal medication used to
anesthetize the patient prior to the start of surgery. This low blood pressure can also
trigger unpleasant side effects such as nausea, vomiting and low Apgar scores for the baby.
Currently there are 2 methods of phenylephrine administration during Cesarean section. One
method is by intermittent bolus and the other is by continuous infusion. It is ideal to have
a regimen for phenylephrine administration that maintains blood pressure without
compromising cardiac output.
In this study, cardiac output and blood pressure will be measured by transthoracic
bioimpedance, which is a new technique of noninvasive continuous cardiac output monitoring.
The hypothesis of this study is that the continuous infusion of phenylephrine will be
equally effective in maintaining blood pressure as compared to the intermittent injection,
and will induce less hemodynamic changes.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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