Clinical Trials Logo
  1. Home
  2. Cardiac Output
  3. NCT00852254

Validation of Minimally Invasive Ultrasound Indicator Dilution Technique in Critically Ill Children

Cardiac Output Clinical Trial

Official title:
Validation of a Novel, Minimally Invasive Ultrasound Indicator Dilution Technique for Measuring Cardiac Index in Critically Ill Children

Clinical Trial Summary

A novel method to measure cardiac index based on ultrasound indicator dilution technology (UIDT) has been developed by Transonic Systems Inc. (Ithaca, NY, USA). The method overcomes many of the limitations that have plagued the existing techniques used to measure cardiac index in critically ill children.

In the proposed investigation, the investigators hope to validate a novel application of an existing technology in critically ill infants and children. The primary aim of this study is to determine the accuracy of cardiac index measured by UIDT when compared to the gold-standard Fick technique. The primary hypothesis is that the average of three consecutive measurements of cardiac index by UIDT will be accurate when compared to the Fick technique. Secondary aims will be to determine the precision of the measurement, the feasibility of the technique with regards to time required and any complications encountered. An exploratory secondary aim of this study is to determine whether central blood volume (CBV) derived from indicator transit time (ITT) correlates with central venous pressure (CVP) and echocardiography derived measures of preload.

Clinical Trial Description

n/a

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00852254
Study type Observational
Source Transonic Systems Inc.
Contact
Status Completed
Phase N/A
Start date June 2008
Completion date May 2011
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT04604886 - The Consistency of Cardiac Output Measured by Pulmonary Artery Catheter and LiDCO in Cardiac Surgical Patients N/A
Completed NCT04044157 - Cardiac Output in Children During Anesthesia
Not yet recruiting NCT01678066 - A Prospective Study to Bilaterally Compare a Non-Invasive Cardiac Output Monitor N/A
Completed NCT01001533 - Assess the Ability of Electrical Cardiometry to Trend Hemodynamic Variables During Dexmedetomidine Sedation N/A
Recruiting NCT04926220 - Dynamic Estimation of Cardiac Output in the Operating Room
Not yet recruiting NCT06007196 - Evaluation of Non-invasive Continuous Hemodynamic Measurement From Task Force CORE
Recruiting NCT05648279 - Personalized Hemodynamic Management in High-risk Major Abdominal Surgery N/A
Recruiting NCT06090396 - Non-invasive Cardiac Index in Children
Completed NCT05508711 - Comparability of Transesophageal Echocardiography and FloTrac/Vigileo System Three Different Positions
Completed NCT02438228 - Cardiac Output by Nine Different Pulse Contour Algorithms N/A
Withdrawn NCT00783679 - The Feasibility and Accuracy of Exhaled CO2 to Measure Cardiac Output in Ventilated Patients Without Tracheal Intubation N/A
Completed NCT00996190 - Best Regimen for Phenylephrine Administration During Cesarean Section Phase 4
Active, not recruiting NCT04465201 - The Smart Pump Study N/A
Completed NCT05779683 - Caretaker in the Cardiovascular Intensive Care Unit (CVICU)
Completed NCT04112719 - Assessing Effects of Lateral Tilt on Cardiac Output Using a Non-invasive Technique
Recruiting NCT01781260 - Effect of Prone Position on Liver Blood Flow and Function N/A
Recruiting NCT02156856 - Stroke Volume Analysis During Aortic Valve Replacement Trial N/A
Terminated NCT00920569 - Recirculation, Oxygenator Blood Volume and Cardiac Output Measurements During Extracorporeal Membrane Oxygenation N/A
Recruiting NCT06114147 - Cardiac Flow Measurements in Pregnant Women by Non Invasive Techniques N/A
Completed NCT05365113 - Comparison of Hemodynamic Effects of Two Modalities of Alveolar Recruitment Maneuvers in Major Abdominal Surgery Patients N/A