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Cardiac Output clinical trials

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NCT ID: NCT05122884 Recruiting - Septic Shock Clinical Trials

Milrinone Versus Placebo in Patients With Septic Shock

Start date: December 1, 2021
Phase: Phase 2
Study type: Interventional

Sepsis is one of the most serious healthcare problems, worldwide, and financial burdens. The overall mortality of severe sepsis/septic shock was 44.5-52.6%. A common cause of death is refractory shock and multi-organ failure. Myocardial dysfunction is a relatively common complication of septic shock. This causes a decrease in the amount of cardiac output, resulting in insufficient blood supply to the organ and multi-organ failure and lead to death Early goal-directed therapy began to use dobutamine in patients with septic shock Sepsis Survival Campaign Guideline 2016 recommended drug is dobutamine and an alternative drug is milrinone in septic shock patients with clinical signs of poor tissue perfusion.

NCT ID: NCT05080023 Recruiting - Cardiac Output Clinical Trials

Impact of Enhanced External Counterpulsation (EECP) on Cardiac Force Index

Start date: February 22, 2022
Phase:
Study type: Observational [Patient Registry]

Regular exercise can prevent cardiovascular disease, but there is also a risk of sudden cardiac death. Exercise-related sudden death often occurs unconsciously and there is no relevant monitoring mechanism. The patent of the Cardiac Force Index (CFI), invented by Professor Chu, is a method to detect the state of cardiac motion. Recent studies have confirmed Enhanced External Counterpulsation (EECP) can increase cardiopulmonary fitness and maximal oxygen consumption. Our aim is to investigate the differences and effects of CFI between two groups with and without 4 weeks of EECP intervention, therefore, to find out the relationship between CFI and maximum oxygen consumption (VO2max). Methods: A pre and post-test control group was designed. A total of 53 military students (33 males and 20 females) were recruited and divided into intervention and control groups. A 2000-meter running and maximum oxygen consumption tests were performed pre and post-test. The intervention group was conducted a 4 week (3 times per week/30 minutes) EECP intervention.

NCT ID: NCT04941248 Recruiting - Cardiac Output Clinical Trials

Total-body 13N-NH3 PET/CT to Study the Blood Perfusion in Whole Body

Start date: June 27, 2021
Phase:
Study type: Observational

The aim of our study is to analyze and quantitate whole-body blood perfusion by total-body 13N-NH3 PET/CT(uEXPLORER), and evaluate the influence to other organs caused by the decreased cardiac function.

NCT ID: NCT04926220 Recruiting - Surgery Clinical Trials

Dynamic Estimation of Cardiac Output in the Operating Room

TRIPLEFLOW
Start date: September 15, 2021
Phase:
Study type: Observational

During major surgery, it is recommended to monitor invasive arterial blood pressure and cardiac output (CO) during hemodynamic interventions (fluid challenge or vasopressors). Esophageal Doppler is currently considered as the reference method for monitoring cardiac output in the operating room. The PRAM method (pressure recording analytical method) with the MostCareUp monitor (Vytech, Padova, Italy) and the LTIA method (long time interval analysis) allow cardiac output estimation derived from non-calibrated arterial pressure waveform analysis. Few studies have looked at relative changes in cardiac output during hemodynamic intervention with these two methods. The aim of this study is to compare the relative changes in cardiac output during hemodynamic interventions as measured using PRAM and LTIA methods, compared to esophageal Doppler.

NCT ID: NCT04685733 Completed - Blood Pressure Clinical Trials

Caretaker Hemodynamic Parameters Validation

Start date: February 1, 2018
Phase:
Study type: Observational

Comparison studies comparing hemodynamic parameters provided by the Caretaker against respective Gold Standard references.

NCT ID: NCT04604886 Recruiting - Cardiac Surgery Clinical Trials

The Consistency of Cardiac Output Measured by Pulmonary Artery Catheter and LiDCO in Cardiac Surgical Patients

Start date: September 30, 2020
Phase: N/A
Study type: Interventional

1. To evaluate the consistency of cardiac output measured by pulmonary artery catheter and LiDCO in cardiac surgical patients 2. To evaluate whether different hemodynamic monitoring methods can accurately detect the trend of cardiac output changes

NCT ID: NCT04465201 Active, not recruiting - Cardiac Output Clinical Trials

The Smart Pump Study

Start date: November 2, 2020
Phase: N/A
Study type: Interventional

To demonstrate that the Impella® Hemodynamic Platform (the "Study Device") is safe, and measurements obtained are as good as currently used methods. These measurements include how much pressure the heart is generating and how much blood your heart is pumping during the PCI.

NCT ID: NCT04265924 Completed - Cardiac Output Clinical Trials

FIO2 Influences SvO2 Interpretation and Fick-based Cardiac Output Assessment

Start date: December 1, 2015
Phase: N/A
Study type: Interventional

In this study, the investigators sought to clarify the influence of FIO2 levels on the variables in the Fick equation and then assessed the influence of each variable on the accuracy of Fick-CO measurements in patients undergoing cardiac surgery.

NCT ID: NCT04112719 Completed - Cardiac Output Clinical Trials

Assessing Effects of Lateral Tilt on Cardiac Output Using a Non-invasive Technique

LATCOIN
Start date: November 1, 2019
Phase:
Study type: Observational

In pregnant term patients, we intent to use a non invasive cardiac output monitor to detect the changes in cardiac output as the patient is being placed in different positions. The patient will be placed on her back, flat, and in left lateral tilt at two different angles. Measurements of cardiac output will be recorded.

NCT ID: NCT04068233 Completed - Cardiac Output Clinical Trials

Impact of Pacing Mode and Diastolic Function on Cardiac Output

PADIAC
Start date: June 26, 2019
Phase: N/A
Study type: Interventional

Background It is known from previous research that in patients with complete AV (atrioventricular) block and pacemaker stimulation stroke volume and cardiac output are higher with AV-synchronous than with AV-dyssynchronous pacing. However, the extent to which patients profited from AV-synchronous stimulation varied substantially. Aim of the study Aim of this study is to systematically analyze the impact of diastolic function and other echo parameters on the difference of stroke volumes/cardiac output between AV-synchronous and AV-dyssynchronous pacing modes. Methods Patients fulfilling the entry criteria will be enrolled (two-chamber pacemaker of any vendor eligible) in this monocentric, prospective, interventional study. Baseline data will be collected with a standardized questionnaire. During an echo examination, parameters of diastolic, systolic and atrial function will be assessed. Then, the stroke volume/cardiac output will be measured twice in each patient, once with AV-synchronous and once with AV-dyssynchronous pacing. Therefore, each patient will represent their own control. It will be randomized (coin tossing) which stimulation mode is first and which is second (sonographer and patient will be blinded). Descriptive statistics will be applied and regression models will be fitted to explore the data.