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Cardiac Adverse Reactions Related to Immune Checkpoint Inhibitor in NSCLC Patients

Cardiac Event Clinical Trial

Official title:
A Prospective Study of Cardiac Adverse Reactions Related to Immune Checkpoint Inhibitor in Non-Small Cell Lung Cancer Patients

Clinical Trial Summary

This is a prospective, open label, single arm study. A total of 300 patients with primary non-small cell lung cancer treated with PD-1/PD-L1 immune checkpoint inhibitors(ICIs) are expected to included . All patients will follow up for at least 1 year. Patients with cardiac adverse reactions after PD-1/PD-L1 immune checkpoint inhibitor treatment at admission or during the subsequently follow-up period will randomly assigned a random number to each patient by computer random sequence. Patients with odd random number will treat with RASI（renin-angiotensin system inhibitors）, and those with even random number will treat with ARNI（angiotensin-receptor-neprilysin inhibitor）.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04473703
Study type Observational
Source Shanghai Chest Hospital
Contact Yunhua Xu
Phone 86-021-22200000
Email yhxu@shchest.org
Status Not yet recruiting
Phase
Start date August 1, 2020
Completion date August 1, 2023
View Details
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