Cardiac Event Clinical Trial
— PHOXEYOfficial title:
Pharmacokinetics of Post Operative Cefuroxime in Infants Undergoing Cardiac Surgery
NCT number | NCT02850250 |
Other study ID # | PHOXEY |
Secondary ID | |
Status | Withdrawn |
Phase | |
First received | |
Last updated | |
Start date | July 2018 |
Est. completion date | October 2019 |
Verified date | January 2019 |
Source | Alder Hey Children's NHS Foundation Trust |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
- To evaluate plasma concentrations of Cefuroxime in this patient population
- To determine if certain pathophysiological and/or iatrogenic conditions alter the
pharmacokinetics in this patient group.
- To develop a rational physiological population pharmacokinetic model that describes
plasma concentrations of medications in these patients.
Status | Withdrawn |
Enrollment | 0 |
Est. completion date | October 2019 |
Est. primary completion date | October 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A to 3 Months |
Eligibility |
Inclusion Criteria: - Age from birth (>37 weeks gestation) to < 3 months - Patients scheduled for congenital cardiac surgery and require cardiopulmonary bypass and intensive care admission post operatively in Alder Hey Children's Hospital - Prescription of studied medications as per standard hospital policy. - Intra-arterial catheter suitable for study sampling in situ. - Informed consent by the parent or a legally authorised representative to participate in the study and to store specimens for immediate and future analysis. Exclusion Criteria: - No written informed consent - Investigator's concerns - Non English speaking - No intra-arterial catheter |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Alder Hey Children's NHS Foundation Trust |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Plasma concentrations | To measure plasma concentrations of Cefuroxime in this patient population | 12 months |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02814084 -
Prevena Incision Management
|
N/A | |
Not yet recruiting |
NCT05897710 -
Virtual World-Based Cardiac Rehabilitation
|
N/A | |
Recruiting |
NCT05200078 -
Deep Inspiration Breath-hold Radiotherapy for Left-sided Breast Cancer
|
||
Recruiting |
NCT05040750 -
Correlation Between Cardiac Markers and Severity of COVID-19
|
||
Completed |
NCT05710796 -
AN OBSERVATIONAL STUDY ON CARDIOVASCULAR INVOLVEMENT IN COVID RECOVERED PATIENTS
|
||
Recruiting |
NCT04573049 -
The Effectiveness and Safety of Levosimendan in Patients With Severe Aortic Stenosis and Heart Failure Undergoing Transcatheter Aortic Valve Replacement
|
Phase 4 | |
Not yet recruiting |
NCT03899298 -
Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions
|
Phase 1 | |
Terminated |
NCT03208023 -
RESIPI for Reducing Perioperative Major Adverse Cardiac Events
|
N/A | |
Completed |
NCT05349708 -
Telehealth Home-monitoring for Frailty in Cardiac Surgery
|
N/A | |
Completed |
NCT04596163 -
Transversus Thoracis Muscle Plane Block for Sternotomy Pain in Cardiac Surgery
|
N/A | |
Not yet recruiting |
NCT04696523 -
Effect of Xenon on Brain Injury After Aneurysmal Subarachnoid Hemorrhage
|
Phase 2 | |
Completed |
NCT03916861 -
BIA Versus Physician Adjustment in Acute Kidney Injury Patients Requiring Renal Replacement Therapy
|
N/A | |
Completed |
NCT03407573 -
Restrictive vs Liberal Transfusion Strategy on Cardiac Injury in Patients Undergoing Surgery for Fractured Neck Of Femur
|
N/A | |
Active, not recruiting |
NCT05449769 -
Supporting Cardiac Rehabilitation With eNutriCardio
|
N/A | |
Completed |
NCT04156594 -
Preoperative Self-assessment for Cardio-pulmonary Risk Stratification
|
||
Enrolling by invitation |
NCT04002531 -
A One Visit Follow Up of Adults With Fabry Disease Who Started Long-term Enzyme Replacement Therapy As Children
|
N/A | |
Recruiting |
NCT05443321 -
Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes
|
N/A | |
Completed |
NCT01830023 -
Vitality Trial - Sampling Examination Data
|
N/A | |
Completed |
NCT04749147 -
Color Priming and Patient Decision-Making in the Emergency Department: Priming "Threat" in Patients With Low-Risk Chest Pain
|
N/A | |
Recruiting |
NCT05288894 -
Repaired Tetralogy of Fallot Italian Registry
|