Dexamethasone for Cardiac Surgery Trial

Status Completed

Clinical Trial Summary

This is a multicenter, randomized, double-blind trial, comparing clinical outcomes after the administration of high-dose dexamethasone versus placebo in patients undergoing heart surgery with the use of cardiopulmonary bypass. The primary endpoint is the occurrence of major complications (including all-cause mortality, myocardial infarction, stroke, renal failure, and prolonged mechanical ventilation) in the first 30 days after surgery.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Cardiac Diseases
Heart Diseases
Postoperative Complications
Systemic Inflammatory Response Syndrome

Clinical Trial Details

NCT number	NCT00293592
Study type	Interventional
Source	UMC Utrecht
Contact
Status	Completed
Phase	N/A
Start date	May 2006
Completion date	December 2012

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT03181620` - Sedation Administration Timing: Intermittent Dosing Reduces Time to Extubation	N/A
Recruiting	`NCT04205058` - Coffee After Pancreatic Surgery	N/A
Completed	`NCT06425601` - A Comparison of Silicone Versus Polyvinylchloride (PVC) Drains Following VATS Lobectomy	N/A
Completed	`NCT02565420` - Saline Versus Lactated Ringer's Solution: The SOLAR Fluid Trial	N/A
Recruiting	`NCT04519593` - ABSOLUTELY: A Temporary Uterine Blood Supply Occlusion for Laparoscopic Myomectomy in Patients With UTErine LeiomYoma	N/A
Completed	`NCT03662672` - Rib Raising for Post-operative Ileus	N/A
Completed	`NCT03787849` - Epigenetics in PostOperative Pediatric Emergence Delirium	N/A
Active, not recruiting	`NCT05886387` - a Bayesian Analysis of Three Randomised Clinical Trials of Intraoperative Ventilation
Not yet recruiting	`NCT06351475` - Efficacy of Intraoperative Use of 20% Albumin Combined With Ringer Lactate Versus Ringer Lactate During Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy	N/A
Not yet recruiting	`NCT05052021` - The South African Coronavirus Disease of 2019 (COVID-19) Surgical Outcomes Study
Not yet recruiting	`NCT03639012` - Outcomes of Carbohydrate Loading Paediatric Patients Preoperatively for Tonsillectomy and Adenoidectomy	N/A
Not yet recruiting	`NCT03591432` - A Trial Comparing Transnasal humidiﬁed Rapid insufﬂation Ventilatory Exchange (THRIVE) and Apneic Oxygenation With Facemask Ventilation in Elderly Patients Undergoing Induction of Anaesthesia.	N/A
Not yet recruiting	`NCT03275324` - Use of Integrated Pulmonary Index to Predict Post-Operative Respiratory Adverse Events in High Risk Patients	N/A
Recruiting	`NCT02763878` - Uncut Roux-en-y Anastomosis Reduce Postoperative Complication and Improve Nutritional Status After Distal Gastrectomy	Phase 3
Completed	`NCT02947789` - Predictive Model for Postoperative Mortality	N/A
Completed	`NCT02891187` - Visits Versus Telephone Calls for Postoperative Care	N/A
Completed	`NCT02766062` - Effects of Propofol and Sevoflurane on Early POCD in Elderly Patients With Metabolic Syndrome	N/A
Not yet recruiting	`NCT02542423` - Endocan Predictive Value in Postcardiac Surgery Acute Respiratory Failure.	N/A
Recruiting	`NCT01934049` - Postoperative Recovery in Elderly Patients Undergoing Hip Hemi-arthroplasty	Phase 4
Enrolling by invitation	`NCT01744938` - Preoperative Biliary Drainage for the Lower Malignant Obstructive Jaundice	Phase 3