Clinical Trials Logo
  1. Home
  2. Cardiac Catheterization
  3. NCT04258007

Sugammadex Versus Neostigmine in Pediatric Less Than Two Years Undergoing Cardiac Catheterization

Cardiac Catheterization Clinical Trial

Official title:
Recovery Profile of Sugammadex Versus Neostigmine in Pediatric Patients Undergoing Cardiac Catheterization: a Randomized Double-blind Study

Clinical Trial Summary

This study hypothesizes that Sugammadex may has more appropriate recovery profile than neostigmine in pediatric cardiac patients undergoing cardiac catheterization. In pediatric cardiac patients, clear and rapid recovery (fast-tracking) is required to maintain hemodynamic within the normal physiological values which may be saved by sugammadex

Clinical Trial Description

There are numerous advantages of early tracheal extubation otherwise known as fast-tracking following anesthesia for congenital heart disease (CHD) Early tracheal extubation not only eliminates the potential morbidity related to an endotracheal tube and mechanical ventilation such as atelectasis, accumulation of secretions, nosocomial infections, and the potential for airway trauma, it also limits the need for sedation and the antecedent adverse effects including respiratory and hemodynamic depression, tolerance, withdrawal, and delirium. Most importantly, the shift from positive pressure to spontaneous ventilation augments cardiovascular function and improves preload. Reversal of neuromuscular blockade is a fundamental aspect of emergence from general anesthesia. Historically, the only option to actively reverse blockade will be to administer anticholinesterase inhibitors, which are unable to reverse deep neuromuscular blockade. They are also associated with a variety of cholinergic side effects, including bradycardia, nausea, and increased secretions, which require concomitant administration of an anticholinergic agent, with its own adverse effects. Sugammadex is a newer, selective relaxant binding agent ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04258007
Study type Interventional
Source Mansoura University
Contact
Status Completed
Phase N/A
Start date January 27, 2020
Completion date November 18, 2020
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT05539092 - The Effect of Changing Angle of Bed on Pain Severity and Vascular Complications Among Cardiac Catheterization Patients N/A
Completed NCT02074527 - CHAIN_brazilian Registry of Congenital HeArt Disease INtervention and Angiography
Completed NCT01157338 - Clinical Significance of Retinal Emboli During Diagnostic and Therapeutic Cardiac Catheterization N/A
Terminated NCT00850473 - PET/CT Study in the Diagnosis of Coronary Plaque N/A
Completed NCT03645837 - Rapid Clamp Release Post Trans-radial Cardiac Catheterization N/A
Completed NCT04404257 - Reduce Radiation Exposure in Fluoroscopic Interventions Evaluation N/A
Recruiting NCT03555500 - Fasting or Non Fasting for Cardiac Catheterization N/A
Not yet recruiting NCT06134141 - The Outcome of Interventional Cardiac Catheterization In Pediatric Cardiology Unit, Assiut University Heart Hospital
Recruiting NCT05941013 - Ultrasound-detectable Endotracheal Tube: a Feasibility Study N/A
Recruiting NCT05632640 - Post Anesthesia Care Unit (PACU) Weighted Blanket Study N/A
Unknown status NCT00838175 - Characteristics Predictive of Success and Complications in the Use of Suture-Mediated Closure of Femoral Venous Access N/A
Completed NCT03243942 - Noninvasive, Subharmonic Intra-Cardiac Pressure Measurement Phase 2
Completed NCT01155167 - Topical Radial Artery Vasodilation Phase 2/Phase 3
Withdrawn NCT00825331 - Improvement of Periprocedural Guidewire Management for Cardiac Catheterization (PTCA) N/A
Recruiting NCT05225077 - Short-term Use of Dapagliflozin to Protect Kidney Function in CKD Patients Phase 4
Completed NCT05117359 - Transcatheter Para-Valvular Leak Closures
Recruiting NCT00849940 - Validation of Brain Oxygenation Monitor on Pediatric Patients N/A
Active, not recruiting NCT05364463 - Effect of Reactive Hyperemia and Ultrasound-guided Puncture on the Success Rate of Radial Artery Cannulation (RadialHUS) N/A
Completed NCT03245255 - Noninvasive Real-time Intracardiac Pressure Measurements Using Subharmonic Ultrasound Phase 2
Enrolling by invitation NCT05628779 - Evaluating Edge-to-edge Transcatheter Tricuspid Valve Repair in Patients With Severe Symptomatic Tricuspid Regurgitation N/A