Clinical Trial Details
— Status: Completed
Administrative data
| NCT number |
NCT02494414 |
| Other study ID # |
AOR12068 |
| Secondary ID |
|
| Status |
Completed |
| Phase |
|
| First received |
|
| Last updated |
|
| Start date |
July 24, 2015 |
| Est. completion date |
January 22, 2021 |
Study information
| Verified date |
April 2021 |
| Source |
Assistance Publique - Hôpitaux de Paris |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Observational
|
Clinical Trial Summary
Early prognosis of cardiac arrest - nearly 40000 new cases per year in France - has been
extensively studied, highlighting a poor outcome (less than 8% at hospital discharge).
However, little is known on mid and long-term prognostic factors and how these patients do
survive from the event.
Using a regional cohort, the aim of the study is to describe long-term survival rate of
cardiac arrest survivors, and to assess the influence of treatment strategies on survival and
functional outcome.
Description:
The collection of clinical and biological data of patients who experienced cardiac arrest and
survive from hospital, including a regular follow-up with qualitative data (functional,
neurological and quality of life) may provide important benchmark on the evolution of these
patients and on the impact of acute interventions (such as cardio-pulmonary resuscitation,
defibrillation, emergent coronary revascularization, neuroprotective treatments).
Using a large identified cohort of survivors of cardiac arrest, we aim to describe the
qualitative long-term prognosis of these cardiac arrest patients (functional, neurological
and quality of life status). Secondarily, we intend to identify the long-term prognostic
factors, and particularly the role of early interventions, using a long-term and qualitative
combined endpoint (vital status, functional scales, SF36).
This project is observational and will include all patients over 18 admitted alive after
non-traumatic cardiac arrest in the area of Ile-de-France (France), whatever the cause of the
cardiac arrest. Patients or their proxies, refusing their participation, will not be
included.
We will collect all pre- and in-hospital information related to the event and performs
prospectively interviews at 3 months and every year anniversary. The questionnaire will
include vital status, cardiovascular events, medication and a complete qualitative report
(SF36, ADL scale, OPC, CPC, social-professional activities).
This project will provide important data over time on the evolution of these patients.
Findings will help in measuring the role of different strategies on long-term prognosis and
consequently improve the overall management of cardiac arrest.
