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Echocardiographic Characterization of Cardiac Amyloidosis: an Observational Study — Echo-AMY  

Cardiac Amyloidosis Clinical Trial

Official title:
Echocardiographic Characterization of Cardiac Amyloidosis: an Observational Study

Clinical Trial Summary

This is a mono-center observational ambispective study in which patients with cardiac amyloidosis evaluated at our institution will be enrolled. The primary aim is to investigate echocardiographic findings, particularly using advanced echocardiographic techniques, such as two- and three-dimensional speckle-tracking analysis, that may be helpful in the differential diagnosis between cardiac amyloidosis and other cardiomyopathies with hypertrophic phenotype. Secondary aims are: 1) to evaluate the reversibility of myocardial damage, assessed by echocardiography, in response to a newly available specific treatment for patients with transthyretin-related cardiac amyloidosis (tafamidis ) and its correlation with the clinical response 2) to investigate potential novel echocardiographic predictors of adverse cardiovascular outcomes.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05760287
Study type Observational
Source Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Contact Francesca Graziani, MD
Phone 00390630154432
Email francesca.graziani@policlinicogemelli.it
Status Recruiting
Phase
Start date December 9, 2022
Completion date February 2, 2031
View Details
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