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NCT04985357 Clinical Trial

Defining the Clinical Potential of Mass Response as a Biomarker for Patient Tumor Sensitivity to Drugs

Carcinoma, Non-Small-Cell Lung Clinical Trial

Official title:
Defining the Clinical Potential of Mass Response as a Biomarker for Patient Tumor Sensitivity to Drugs

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT04985357
Other study ID # TRV-002
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date June 2024
Est. completion date May 2030

Study information
Verified date December 2023
Source Travera Inc
Contact Mark Stevens, Ph.D.
Phone 6172999784
Email trv002@travera.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The primary objective of this study, sponsored by Travera in Massachusetts, is to validate whether the mass response biomarker has potential to predict response of patients to specific therapies or therapeutic combinations using isolated tumor cells from varying cancers and biopsy formats.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 630
Est. completion date May 2030
Est. primary completion date May 2028
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Sample collection or biopsy of tumor is clinically indicated as part of SOC - Prior to preceding onto therapy for treatment Exclusion Criteria: - Unable to obtain sufficient sample

Study Design

Related Conditions & MeSH terms

  • AML
  • Anus Neoplasms
  • Ascites
  • Breast Neoplasms
  • Carcinoma
  • Carcinoma Breast
  • Carcinoma Cervix
  • Carcinoma of Esophagus
  • Carcinoma of Lung
  • Carcinoma of the Appendix
  • Carcinoma of the Head and Neck
  • Carcinoma of the Oral Cavity
  • Carcinoma of the Oropharynx
  • Carcinoma of the Vulva
  • Carcinoma of Unknown Primary
  • Carcinoma Prostate
  • Carcinoma, Ductal
  • Carcinoma, Hepatocellular
  • Carcinoma, Neuroendocrine
  • Carcinoma, Non-Small-Cell Lung
  • Carcinoma, Ovarian Epithelial
  • Carcinoma, Pancreatic
  • Carcinoma, Renal Cell
  • Carcinoma, Small Cell
  • Carcinoma, Small Cell Lung
  • Carcinoma, Thymic
  • Cholangiocarcinoma
  • Esophageal Neoplasms
  • Lung Neoplasms
  • Malignant Ascites
  • Malignant Pleural Effusion
  • Mesothelioma
  • Multiple Myeloma
  • Multiple Myeloma in Relapse
  • Pleural Effusion
  • Pleural Effusion, Malignant
  • Prostatic Neoplasms
  • Small Cell Lung Carcinoma
  • Stage III Breast Cancer
  • Stage III Lung Cancer
  • Stage IV Breast Cancer
  • Stage IV Lung Cancer
  • Thymoma
  • Urinary Bladder Neoplasms
  • Vulvar Neoplasms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Travera Inc

Outcome
Type Measure Description Time frame Safety issue
Primary Best overall response (BOR) The best overall response to therapy over 24 months will be captured for correlation with test outcomes. up to 24 months
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