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Carcinoma in Situ clinical trials

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NCT ID: NCT00247169 Completed - Clinical trials for Cervical Intraepithelial Neoplasia

Vaginal Progesterone in the Treatment of Cervical Dysplasia Grade I and II

Start date: August 2004
Phase: Phase 2
Study type: Interventional

The investigators want to test whether treatment with a natural progesterone intravaginally increases the cure rate of cervical intraepithelial neoplasia grade I and II.

NCT ID: NCT00237562 Completed - Clinical trials for Cervical Intraepithelial Neoplasia

Feasibility of the Management of Severe Cervical Dysplasia in a Single Visit

Start date: July 1999
Phase: Phase 3
Study type: Interventional

1. Implement a single-visit program (SVP) for cervix cancer prevention in clinics serving a multi-ethnic population of women; 2. Set up an efficient system for interpretation of Pap smears for patients in the SVP that will minimize waiting time; 3. Determine the follow-up rates and compare them between women assigned to the SVP and a usual care program (UCP); 4. Determine satisfaction and compare it between women assigned to the SVP and the UCP; 5. Determine the cost-effectiveness and compare it between the SVP and UCP

NCT ID: NCT00225927 Completed - Clinical trials for Breast Cancer Invasive Nos

Trial Comparing Radioactive Seed Localization to Standard Procedure for Non-palpable Breast Cancers

Start date: June 2004
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether a new surgical technique (radioguided seed localization) for localizing nonpalpable breast tumours is better than the standard technique (needle localization).

NCT ID: NCT00201370 Completed - Cervical Cancer Clinical Trials

A Multi-center Survey of HPV in Cervical Intraepithelial Neoplasia (CIN) With Longitudinal Follow-up of LSIL Cases

Start date: August 1999
Phase: N/A
Study type: Observational

The aims of this study are: 1. Surveillance of the prevalence of HPV infection in ASCUS, AGCUS and SIL cases pooled from medical centers in Taiwan and analysis of the related epidemiological factors. 2. Providing a better understanding of the natural history of HPV infection with its correlation with pathologic changes through a longitudinal follow-up of LSIL cases.

NCT ID: NCT00190983 Completed - Clinical trials for Cervical Intraepithelial Neoplasia

A Trial for Patients With Advanced/Recurrent Cervical Cancer

Start date: February 2005
Phase: Phase 2
Study type: Interventional

This phase II trial is studying the antitumor activity of single agent pemetrexed 900mg/m2 IV over 10 minutes in patients with recurrent cervical cancer.

NCT ID: NCT00183963 Terminated - Breast Carcinoma Clinical Trials

A Pilot Clinical Trial to Evaluate the Biological Activity of Fulvestrant in Breast Ductal Carcinoma in Situ (DCIS)

Start date: August 2006
Phase: Phase 2
Study type: Interventional

The subjects in this trial have been diagnosed as having a pre-cancerous disease of the breast called ductal carcinoma in situ (DCIS). This condition is associated with the development of breast cancer in up to 50% of cases. The subjects are being asked to participate in this research study. They are being offered voluntary admission to this study to test the effects of a new investigational drug called Fulvestrant (Faslodex). This drug is approved by the United States Food and Drug Administration (FDA) for the treatment of advanced breast cancer but has not been approved for the treatment of DCIS. However, the FDA has given permission for the drug to be tested in this study. The purpose of this study is to find out if Fulvestrant has any effect on the subject's precancerous changes by comparing samples taken before and after receiving Fulvestrant.

NCT ID: NCT00178113 Completed - Clinical trials for Prostatic Intraepithelial Neoplasia

A Pilot Study of Lycopene Supplementation in Prostatic Intraepithelial Neoplasia

Start date: July 2003
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine whether dietary lycopene supplementation lowers serum prostate specific antigen(PSA) in men with high grade intraepithelial neoplasia (HGPIN).

NCT ID: NCT00165256 Active, not recruiting - Clinical trials for Ductal Carcinoma in Situ of the Breast

Wide Excision Alone as Treatment for Ductal Carcinoma in Situ of The Breast

Start date: May 1995
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if wide excision (surgical removal) alone is adequate treatment for small, grade 1 or 2 ductal carcinoma in situ (DCIS) of the breast.

NCT ID: NCT00156026 Completed - Clinical trials for Cervical Intraepithelial Neoplasia

Immediate Treatment vs Colposcopic Follow-up for Biopsy-Proven CIN 1

Start date: November 2000
Phase: Phase 3
Study type: Interventional

This study looks at immediate treatment of a cervix with CIN 1 versus regular six-month follow-up with colposcopy and treatment if CIN 1 progresses.

NCT ID: NCT00154089 Completed - Clinical trials for Cervical Intraepithelial Neoplasia

A Pilot Study of EM-1421 for the Treatment of Cervical Intraepithelial Neoplasia

Start date: November 2004
Phase: Phase 1/Phase 2
Study type: Interventional

The primary objective of this study is to determine pilot safety and efficacy data for a topical formulation of EM-1421 applied to the cervix of patients with CIN 1, 2, or 3.