Effects of Different Fresh Gas Flows on Carboxyhemoglobin Levels

Carboxyhemoglobinemia Clinical Trial

Official title:

Effects of Different Fresh Gas Flows on Carboxyhemoglobin Levels: Noninvasive Carbon Monoxide Monitoring

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04832256
• Other study ID #: 2015-67-07/07
• Status: Completed
• Start date: January 1, 2016
• Est. completion date: June 1, 2019

Study information

• Verified date: May 2022
• Source: Zonguldak Bulent Ecevit University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

To observe the effect of different fresh flows (1 L / min and 4 L / min) on the carboxyhemoglobin level non-invasively and continuous measurement and to determine the contribution of smoking to the intraoperative carbon monoxide accumulation.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 64
• Est. completion date: June 1, 2019
• Est. primary completion date: December 31, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• ASA I-II
• Undergo 2-4 hours of elective surgery

Exclusion Criteria:

• Cardiovascular disease
• diabetes mellitus
• kidney, liver failure
• chronic obstructive pulmonary disease
• patients with opioid sensitivity
• morbidly obese
• personal or family history of malignant hyperthermia
• history of prolonged recovery from anesthesia
• alcohol addicted
• pregnant and breastfeeding women patients allergic to study drugs

Related Conditions & MeSH terms

• Carbon Monoxide Poisoning
• Carboxyhemoglobinemia
• Fresh Flow

Intervention

Device:
• Radical-7 Pulse CO-Oximeter
COHb measurement monitoring from finger pulp with a non-invasive measurement device called Masimo Radical-7 Pulse co-oximeter (Masimo Corporation, Irvine, USA)

Locations

Country	Name	City	State
Turkey	Zonguldak Bülent Ecevit University Medicine Faculty	Zonguldak	Kozlu

Sponsors (1)

Lead Sponsor	Collaborator
Zonguldak Bulent Ecevit University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	effects of different fresh gas flows on carboxyhemoglobin levels	To observe the effect of different fresh flows (1 L / min and 4 L / min) on the carboxyhemoglobin level by non-invasive and continuous measurement.	during surgery
Secondary	effects of smoking on carbon monoxide accumulation.	to determine the contribution of smoking to intraoperative carbon monoxide accumulation.	during surgery