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CANVAS clinical trials

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NCT ID: NCT05621200 Completed - Clinical trials for Multiple System Atrophy

Transcranial Alternating Current Stimulation (tACS) in Patients With Ataxia

SCAtACS
Start date: January 28, 2021
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate the effects on motor and cognitive performance of transcranial alternating current stimulation (tACS) compared to transcranial direct current stimulation (tDCS) and placebo stimulation (sham) in patients with neurodegenerative ataxia to identify a possible rehabilitation protocol.

NCT ID: NCT04153110 Completed - Clinical trials for Multiple System Atrophy

Cerebello-Spinal tDCS as Rehabilitative Intervention in Neurodegenerative Ataxia

SCA02
Start date: December 1, 2018
Phase: N/A
Study type: Interventional

Neurodegenerative cerebellar ataxias represent a group of disabling disorders which currently lack effective therapies. Cerebellar transcranial direct current stimulation (tDCS) is a non-invasive technique, which has been demonstrated to modulate cerebellar excitability and improve symptoms in patients with cerebellar ataxias. In this randomized, double-blind, sham-controlled study followed by an open-label phase, the investigators will evaluate whether a repetition of two-weeks' treatment with cerebellar anodal tDCS and spinal cathodal tDCS, after a three months interval, may further outlast clinical improvement in patients with neurodegenerative cerebellar ataxia and can modulate cerebello-motor connectivity, at short and long term.