Clinical Trials Logo
  1. Home
  2. Cannabis
  3. NCT05436236
  4. Details
NCT05436236 Clinical Trial

Effect of Cannabis (Marijuana) on Stomach Emptying Before Surgery

Cannabis Clinical Trial

Official title:
Cannabis Consumption Effect on Gastric Volumes

Clinical Trial Details — Status: Withdrawn

Administrative data
NCT number NCT05436236
Other study ID # 2204-15
Secondary ID
Status Withdrawn
Phase
First received
Last updated
Start date December 1, 2024
Est. completion date December 1, 2026

Study information
Verified date February 2024
Source The Guthrie Clinic
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The purpose of this research is to study the effect of cannabis (marijuana) on gastric (stomach) emptying before surgery. The study will include people who use cannabis (study group) and people who do not use cannabis (control group).

Description:

About 108 people will take part in this study (54 in the study group and 54 in the control group). Subjects will have an ultrasound of the abdomen before their scheduled surgery. The ultrasound will determine how much fluid remains in the abdomen. Researchers will also review subjects' medical records and will include: age, body mass index, history of cannabis use including how often and how consumed, reason for surgery, and length of time without eating before surgery.

Recruitment information / eligibility
Status Withdrawn
Enrollment 0
Est. completion date December 1, 2026
Est. primary completion date December 1, 2025
Accepts healthy volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Subjects 18 years and older - Planned surgery at one of two hospitals within the healthcare system - Willing to state if they use or do not use cannabis - Able to read and consent on their own behalf Exclusion Criteria: - Cognitively impaired - Unable to read - Children under the age of 18 - Pregnant women - Pregnancy status will be obtained from the routine pregnancy test performed prior to surgery - History of gastroparesis - Gastric surgeries - Advanced liver or renal dysfunction - Critically ill - Emergent/urgent cases

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
The Guthrie Clinic

Outcome
Type Measure Description Time frame Safety issue
Primary Gastric content volume Gastric content volume as assessed by ultrasound prior to surgery pre-operative
Secondary Frequency of cannabis use number of times per week patient uses cannabis 3 months prior to surgery
Secondary Cannabis use (chronic yes or no) Yes or No for chronic cannabis use 1 year prior to surgery
Secondary Route of cannabis consumption Categories of how cannabis is consumed (smoke, vape, other) 3 months prior to surgery
Secondary Time since last food; Nil per os (NPO) time Length of time patient had no food prior to surgery 24 hours prior to surgery
See also
  Status Clinical Trial Phase
Completed NCT04284813 - Families With Substance Use and Psychosis: A Pilot Study N/A
Completed NCT04199468 - THC and Ketamine Effects in Humans: Relation to Neural Oscillations and Psychosis Phase 1
Completed NCT04587700 - Analgesic Consumption in Chronic Marijuana Users Following Orthopedic Trauma Surgery
Not yet recruiting NCT05899946 - An Integrated Program to Promote Anti-cannabis Messages N/A
Active, not recruiting NCT02735954 - Colorado Marijuana Users Health Cohort
Completed NCT00842985 - Dronabinol Interactions in Humans N/A
Completed NCT04124432 - Behavioral Pharmacology of Cannabis and Nicotine Phase 1
Active, not recruiting NCT04693884 - Cannabis Inhalation: Effects on Cardiovascular Function During Rest and Exercise Early Phase 1
Recruiting NCT03078309 - The Effects of Cannabis on Visual Functions in Healthy and Retinitis Pigmentosa Patients Early Phase 1
Active, not recruiting NCT03560934 - Tetrahydrocannabinol (THC) and Sleep Early Phase 1
Recruiting NCT04704271 - Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study II Phase 1
Withdrawn NCT03245658 - The Effect of Cannabis in Pancreatic Cancer Phase 2
Completed NCT04911127 - Therapeutic Response of Cannabidiol in Rheumatoid Arthritis Phase 1/Phase 2
Not yet recruiting NCT05999383 - Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration Phase 2
Recruiting NCT04429568 - THC Crossover Study N/A
Completed NCT05554146 - Pain Inflammation and Cannabis in HIV N/A
Not yet recruiting NCT05320367 - A Study of Inhaled Cannabidiol in Healthy Occasional Cannabis Users Phase 1/Phase 2
Completed NCT02567344 - Excitatory rTMS to the Left Dorsolateral Pre-Frontal Cortex to Reduce Cannabis-Cue Induced Craving N/A
Terminated NCT03251326 - Nabilone in Cannabis Users With PTSD Phase 1/Phase 2
Completed NCT00176085 - Pharmacokinetics of THCCOOH and Its Acyl-glucuronide After Intravenous Administration of THCCOOH Phase 1