Effect of Cannabis (Marijuana) on Stomach Emptying Before Surgery

Cannabis Clinical Trial

Official title:

Cannabis Consumption Effect on Gastric Volumes

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT05436236
• Other study ID #: 2204-15
• Status: Withdrawn
• Start date: December 1, 2024
• Est. completion date: December 1, 2026

Study information

• Verified date: February 2024
• Source: The Guthrie Clinic
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this research is to study the effect of cannabis (marijuana) on gastric (stomach) emptying before surgery. The study will include people who use cannabis (study group) and people who do not use cannabis (control group).

Description:

About 108 people will take part in this study (54 in the study group and 54 in the control group). Subjects will have an ultrasound of the abdomen before their scheduled surgery. The ultrasound will determine how much fluid remains in the abdomen.

Researchers will also review subjects' medical records and will include: age, body mass index, history of cannabis use including how often and how consumed, reason for surgery, and length of time without eating before surgery.

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. completion date: December 1, 2026
• Est. primary completion date: December 1, 2025
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Subjects 18 years and older

• Planned surgery at one of two hospitals within the healthcare system

• Willing to state if they use or do not use cannabis

• Able to read and consent on their own behalf

Exclusion Criteria:

• Cognitively impaired

• Unable to read

• Children under the age of 18

• Pregnant women - Pregnancy status will be obtained from the routine pregnancy test performed prior to surgery

• History of gastroparesis

• Gastric surgeries

• Advanced liver or renal dysfunction

• Critically ill

• Emergent/urgent cases

Related Conditions & MeSH terms

• Cannabis
• Gastric Emptying
• Marijuana Abuse

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
The Guthrie Clinic

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Gastric content volume	Gastric content volume as assessed by ultrasound prior to surgery	pre-operative
Secondary	Frequency of cannabis use	number of times per week patient uses cannabis	3 months prior to surgery
Secondary	Cannabis use (chronic yes or no)	Yes or No for chronic cannabis use	1 year prior to surgery
Secondary	Route of cannabis consumption	Categories of how cannabis is consumed (smoke, vape, other)	3 months prior to surgery
Secondary	Time since last food; Nil per os (NPO) time	Length of time patient had no food prior to surgery	24 hours prior to surgery