The Study of Pharmacological Treatment Pattern for Cannabis-induced Psychosis

Cannabis Clinical Trial

Official title:

The Study of Pharmacological Treatment Pattern for Cannabis-induced Psychosis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04945031
• Other study ID #: MU-DT/PY-IRB2019/PY114
• Status: Completed
• Start date: November 8, 2019
• Est. completion date: December 31, 2020

Study information

• Verified date: June 2021
• Source: Mahidol University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

A cross-sectional and retrospective chart review study was conducted at the Princess Mother National Institute on Drug Abuse Treatment (PMNIDAT), Thailand. All patients who admitted at PMNIDAT from October 2013 to September 2019 were included. Patients aged 18-65 years who met the International Classification of Disease-10 (ICD-10) criteria of CIP and Had a positive urine test of cannabis were included. Cannabis use is a component cause of psychosis.More than half of symptoms of cannabis-induced psychosis (CIP) were hallucination, delusion, irritable and anxiety. Antipsychotic drug was still a key psychotropic drugs for treatment of CIP. However, antidepressants and benzodiazepines were commonly used for treatment of other symptoms beyond psychotics

Recruitment information / eligibility

• Status: Completed
• Enrollment: 317
• Est. completion date: December 31, 2020
• Est. primary completion date: May 31, 2020
• Gender: All
• Age group: 12 Years and older

Eligibility

Inclusion Criteria:

• Patients = 12 years of age

• Patients who had been diagnosed as Cannabis-induced psychosis by International statistical Classification of Disease and Related Health problem (ICD-10) on 2016 code F12.5

• Patients had history of use of cannabis in medical chart

• Patients had the positive urine screening test of cannabis at the first day of admission

Exclusion Criteria:

• Patients had psychosis from organic psychosis, defined by diagnosis by ICD-10 code F09.6

• Unavailable data for evaluate of outcome especially data of drug use, content of drug use or urine screening test

• Patients who cancel of medical treatment before 7 day after admission.

Related Conditions & MeSH terms

• Cannabis
• Marijuana Abuse

Intervention

Other:
• cannabis
This study is observational study, we recorded history of substance used, symptoms and medication in a medical chart.

Locations

Country	Name	City	State
Thailand	Onrumpha Chuenchom	Thanyaburi	Pathum Thani

Sponsors (1)

Lead Sponsor	Collaborator
Mahidol University

Country where clinical trial is conducted

Thailand, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pharmacological treatment pattern for cannabis-induced psychosis	Pharmacological treatment pattern for cannabis-induced psychosis during admission	30 days
Secondary	Change of Brief psychiatric rating scale (BPRS) form the first day of admission	A high BPRS score is more severe of symptoms than a lower score	Day1, Day 8, Day 15 and Day 22