Cortical Excitability and Role of rTMS in Cannabis Use Disorder

Cannabis Use Disorder, Moderate Clinical Trial

Official title:

Cortical Excitability and Role of rTMS in Cannabis Use Disorder

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04106336
• Other study ID #: rTMS in cannabis use disorder
• Status: Not yet recruiting
• Phase: Early Phase 1
• Start date: October 1, 2019
• Est. completion date: December 30, 2020

Study information

• Verified date: September 2019
• Source: Assiut University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Repetitive transcranial magnetic stimulation (rTMS) and cortical excitability have a role in cannabis use disorder

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 60
• Est. completion date: December 30, 2020
• Est. primary completion date: October 1, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

• 18to 50 years of age

• cannabis use disorder according to DSM 5 definition

• clear consent to participate in study

Exclusion Criteria:

• cardiac peacemaker

• metal implant in the head as participate will be applied to magnetic field of TMS

• current intake of any medication affect cognition (as anti psychotic and anti epileptic)

• current history of neurological , psychiatric or general medical disease .current or previous drug (other than cannabis )or alcohol abuse or participation in another trial during the past 8 weeks .

• age younger than 18 and older than 50 years

Related Conditions & MeSH terms

• Cannabis Use Disorder, Moderate
• Disease
• Marijuana Abuse

Intervention

Device:
• rTMS
Repetitive transcranial magnetic stimulation (rTMS) will be done for cannabis addict

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Determination of role of rTMS for reducing cannabis craving	Incidenc of cannabis craving after rTMS	1 year
Secondary	Estimation of cortical excitability in cannabis addict	Incidence of cannabis craving after cortical excitability	1 year