Salivary Catecholamines in Aphthous Stomatitis (Canker Sores)

Canker Sore Clinical Trial

Official title:

Salivary Catecholamines in Aphthous Stomatitis

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT00556686
• Other study ID #: 200614581
• Status: Withdrawn
• Phase: N/A
• First received: November 8, 2007
• Last updated: April 20, 2015
• Start date: August 2006
• Est. completion date: December 2009

Study information

• Verified date: April 2015
• Source: University of California, Davis
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to examine how compounds produced in patients with canker sores affect wound healing.

Description:

The purpose of this study is to determine if salivary catecholamines are elevated in patients with the disease aphthous stomatitis. The results of this study will be combined with those performed in collaboration with a co-Investigator to understand the effects of catecholamines on mucosal wound healing and oral epithelial cell migration.

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. completion date: December 2009
• Est. primary completion date: December 2009
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Age 18 or older, both genders

• History of recurrent aphthous ulcers with 4 or more episodes per year

Exclusion Criteria:

• History of salivary gland disease including Sjogren's disease, parotitis, and sialolithiasis

• History of benign or malignant salivary gland tumor

• History of celiac disease, ulcerative colitis or Crohn's disease

• Patients on medications that affect salivary flow such as anti-depressants and anti-cholinergic medications

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Canker Sore
• Stomatitis
• Stomatitis, Aphthous

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University of California, Davis

External Links

•   University of California-Davis Department of Dermatology Clinical Research