Effect of Probiotic Bacteria on Oral Candida in Frail Elderly

Status Completed

Clinical Trial Summary

The aim of this study is to investigate the effect of daily intake of the probiotic Lactobacillus Reuteri on the prevalence and counts of oral Candida in frail elderly living in nursery homes.

Clinical Trial Description

The aim of the present study was to investigate the effect of a twice daily intake of lozenges containing probiotic Lactobacillus reuteri on the prevalence and counts of oral Candida in senior residents living in nursery homes. The material consists of 215 elderly persons (range 60 to 102 years) living in 20 different nursery homes in the County of Kronoberg, situated in the southern parts of Sweden. The subjects were consecutively enrolled after informed consent consisting of verbal and written information directed to the individual as well as to their relatives. The study employed a double-blind randomized placebo-controlled design. ;

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Prevention

Related Conditions & MeSH terms

Candidiasis

Clinical Trial Details

NCT number	NCT02391532
Study type	Interventional
Source	University of Copenhagen
Contact
Status	Completed
Phase	N/A
Start date	September 2013
Completion date	June 2015

View Details

See also
Status	Clinical Trial	Phase
Terminated	`NCT01982071` - A Study to Evaluate the Efficacy and Safety of Micafungin Against Invasive Candidiasis or Candidemia	Phase 4
Completed	`NCT01447407` - Effect of Adjuvant & Route of Administration on Safety & Immunogenicity of NDV-3 Vaccine	Phase 1
Not yet recruiting	`NCT00889356` - Evaluate Efficacy, Tolerability & Safety of Combination of Clindamycin and Ketoconazole for the Treatment of Mixed-Type Vaginosis, Bacterial Vaginosis and Candidiasis	Phase 3
Completed	`NCT00105144` - Study of Micafungin in Patients With Invasive Candidiasis or Candidemia	Phase 3
Completed	`NCT00163111` - A Clinical Study Intended To Compare Treatment With Voriconazole To Treatment With Amphotericin Followed By Fluconazole In Patients With Candidemia, A Serious Fungus Infection Of The Blood.	Phase 3
Completed	`NCT00138502` - Funguria in Hospitalized Patients
Not yet recruiting	`NCT04502277` - Bioavailability of Flucanazole	Early Phase 1
Completed	`NCT03203551` - Clinical and Laboratorial Evaluation of the Desinfection Solutions in Candida Species From Total Prostheses and Palate of Total Edentulous.	N/A
Completed	`NCT05044156` - Investigation of the Relationship Between Salivary Histatine-5 Level and Vaginal Candidiasis in Women
Completed	`NCT01322698` - Staging Candidiasis in ICU Patients	N/A
Terminated	`NCT01092832` - A Study Of The Safety, Tolerability And Effective Of Voriconazole For The Treatment Of Serious Candida Infection And Candida Infection Of The Throat In Pediatric Patients	Phase 3
Terminated	`NCT00095316` - Caspofungin Study for Fungal Infections in Adults in Critical Care Settings	Phase 3
Completed	`NCT04122560` - Fluconazole Pharmacokinetics, Including Bioavailability, in Obese Subjects After an Intravenous and Oral Administration	Phase 4
Completed	`NCT02641717` - Validity of Patient-Collected Wet Mounts	N/A
Recruiting	`NCT01253954` - A Multicenter Observational Study of Invasive Candida Infections Among ICU Patients in China	N/A
Completed	`NCT00734539` - Fluconazole Prophylaxis for the Prevention of Candidiasis in Infants Less Than 750 Grams Birthweight	Phase 3
Completed	`NCT00797420` - Pharmacokinetics (PK) Study of a Fluconazole Loading Dose in Infants and Toddlers	Phase 1
Completed	`NCT00001937` - Comparing the Effectiveness of Fluconazole and a New Medicine (FK463) in Preventing Fungal Infections in Bone Marrow Transplant Patients	Phase 3
Completed	`NCT02666716` - Pharmacokinetics of Fluconazole IV as Prophylaxis or Therapy to ICU Patients
Terminated	`NCT00692783` - Incidence of Oral Candidiasis, Prevalence of C. Dubliniensis in HIV Patients and In-vitro Azole Susceptibility	N/A