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Vascular Endothelial Inflammation and Dysfunction in Pediatric Long-term Cancer Survivors

Pediatric Cancer Clinical Trial

Official title:
Vascular Endothelial Inflammation and Dysfunction in Pediatric Long-term Cancer Survivors

Clinical Trial Summary

Survivors of childhood cancer have an increased risk of death from cardiovascular disease due to both the therapies they received while undergoing treatment and diet and lifestyle factors. The nature of cardiovascular risk and the interaction between treatment affects and cardiovascular risk factors is unknown. We propose to study vascular inflammatory markers as well as measure of blood vessel stiffness (both of which are predictive of early heart disease) in 100 pediatric cancer survivors and 100 control children. Characterization of vascular inflammation and stiffness in long-term survivors will allow for the development of future interventions to decrease inflammation through both pharmacologic and lifestyle modifications.

Clinical Trial Description

n/a

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02032121
Study type Interventional
Source University of Miami
Contact
Status Completed
Phase N/A
Start date October 2007
Completion date August 2015
View Details
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