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Low-dose Radiotherapy Combined With Conventional Radiotherapy After Immunotherapy Failure — FL001  

Cancer Patients Clinical Trial

Official title:
A Clinical Study of Low-dose Radiotherapy Combined With Conventional Radiotherapy in Patients With Malignant Tumors After Immunotherapy Failure

Clinical Trial Summary

Response was evaluated according to the Guidelines for Response Criteria for Use in Trials Testing Immunotherapeutics (iRECIST) : ORR-To evaluate the objective effective rate of LDRT combined with SFRT and immunotherapy in patients with malignant tumors after immunotherapy resistance without standard regimens. PFS-To evaluate the progression-free survival (PFS) of patients with advanced malignant tumors after LDRT combined with SFRT and immunotherapy without standard regimens after immunotherapy resistance.DCR-To evaluate the proportion of patients with optimal response to LDRT and SFRT combined with immunotherapy to achieve complete response, partial response, or disease control after no standard regimen was available for immunotherapy resistance.HRQoL, AE and sAE-Evaluation of health related quality of life and safety of post-LDRT combined with SFRT and immunotherapy in patients with malignant tumors. To evaluate the benefit of patients in this trial.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05547282
Study type Interventional
Source Qianfoshan Hospital
Contact JIANDONG ZHANG JD ZHANG, Dr
Phone 13583123486
Email zhangjd165@sina.com
Status Recruiting
Phase N/A
Start date October 1, 2022
Completion date February 1, 2024
View Details
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