Cancer of the Head and Neck Clinical Trial
Official title:
A Prospective Study to Evaluate the Incidence and Patterns of Nausea and Vomiting in Patients Receiving Combined Chemotherapy and Radiation
Verified date | December 2014 |
Source | Thomas Jefferson University |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Institutional Review Board |
Study type | Observational |
Questionnaire study to observe the incidence and pattern or nausea and vomiting in patients receiving combined chemotherapy and radiation. 83% of patients experience radiation therapy-induced vomiting; significant nausea and vomiting could develop with concurrent chemotherapy despite standard anti-nauseous medication prophylaxis.
Status | Completed |
Enrollment | 40 |
Est. completion date | September 2011 |
Est. primary completion date | August 2008 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Concurrent radiation and chemotherapy treatment - Aerodigestive malignancy Exclusion Criteria: - Other causes of vomiting (i.e.gastrointestinal obstruction...) |
Observational Model: Case-Only, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
United States | Thomas Jefferson University | Philadelphia | Pennsylvania |
Lead Sponsor | Collaborator |
---|---|
Thomas Jefferson University | Merck Sharp & Dohme Corp. |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Assess incidence and patterns of nausea and vomiting in patients undergoing concurrent chemotherapy and radiation | week of treatment | No | |
Secondary | Assess the impact of nausea and vomiting on the patients' daily functioning | week of treatment | No | |
Secondary | Study the incidence of mucositis and esophagitis | week of treatment | No |
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