Pancreatico Enteric Anastomosis Post Pancreaticoduodenectomy — PEAPP  

Cancer of Pancreas Clinical Trial

Official title: Comparison Between Blumgart Anastomosis and Cattell Warren Anastomosis in Reduction of Post-Operative Complications After Pancreaticoduodenectomy Procedure

Status Recruiting

Clinical Trial Summary

The aim of this study is to make a step for evaluation and presentation of a safe technique for pancreatico-jejunostomy that help in minimizing post-operative morbidity and mortality in pancreatic cancer patient by comparing Blumgart anastomosis with Cattell warren technique of anastomosis.

Clinical Trial Description

Study Design This study is a randomized prospective clinical trial. Methods of randomization:

Randomized block design

The objective of the study was to evaluate the effect of Blumgart anastomosis versus Cattell Warren techniques for pancreatico-jejunostomy regarding

• Surgical technique

• Peri-operative outcome including

1. Length of hospital stay

2. Post-operative pancreatic fistula

3. ICU admission and stay

4. Operative time

5. Other morbidity and mortality

Data collection:

All data will be collected for each group and will be divided into Patients' factors, intraoperative and postoperative factors. Patients' factors include patients' demographics, co-morbidities, neoadjuvant treatment, Pathology and Biliary drainage. Intra-operative factors include type of Pancreaticoduodenectomy (PD) (Whether classic or PPPD), Operative time in hours and estimated blood loss in ml, pancreatic duct and texture of pancreas. Post-operative factors include the short term post-operative course which will be divided into specific complications (pancreatic leakage, biliary leakage, delayed gastric emptying, 2ry hemorrhage, intra-abdominal collection, deep wound infection, Portal Vein (PV) - Superior Mesenteric Vein (SMV) thrombosis and general surgical complications. ;

Related Conditions & MeSH terms

• Cancer of Pancreas
• Pancreatic Neoplasms

• NCT number: NCT05163977
• Study type: Interventional
• Source: Cairo University
• Contact: Ehab A Abdulmaksoud, Master
• Phone: 01099192044
• Email: ehab.a.abdelmaksoud@cu.edu.eg
• Status: Recruiting
• Phase: N/A
• Start date: June 12, 2021
• Completion date: December 2022