Molecular Biomarkers Predicting Early Development of Endometrial Carcinoma

Status Recruiting

Clinical Trial Summary

Endometrial carcinoma represents the most common gynaecological cancer and the sixth most frequent cancer among women worldwide. The 5-year survival of patients with stage I endometrial carcinoma is 75%-88% versus 50% for stage III or 15% for stage IV disease. Therefore, early detection could improve survival rates. Specifically, in the most prevalent, type 1 endometrial cancer develops from hyperplastic endometrium. The aim of the study was to evaluate the utility of cancer gene mutations from endometrial biopsies towards predicting synchronous or metachronous development of malignant lesions. The aim of the study was to evaluate whether endometrial biopsies could already carry mutations in cancer genes useful for predicting or anticipating subsequent cancer development

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05273099
Study type	Observational
Source	Università degli Studi di Ferrara
Contact	Gennaro Scutiero, MD
Phone	+390532236657
Email	gennaro.scutiero@unife.it
Status	Recruiting
Phase
Start date	March 1, 2022
Completion date	December 2023

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