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Calculi clinical trials

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NCT ID: NCT05082142 Completed - Urologic Diseases Clinical Trials

Tranexamic Acid to Improve Same-day Discharge Rates After Holmium Laser Enucleation of the Prostate (HoLEP)

Start date: September 17, 2021
Phase: Phase 4
Study type: Interventional

This study is designed to assess if there is a significant difference in same day discharge rates after Holmium Laser Enucleation of the Prostate (HoLEP). The investigators attempt to perform HoLEP as a same-day discharge (SDD) procedure, but at Northwestern Memorial, the SDD rate is currently approximately 60%. The limiting factor in SDD is hematuria. Tranexamic acid (TXA) is a clot promoting drug that is commonly used by orthopedic, cardiac and obstetric surgeons to prevent bleeding. The primary outcome will be to assess if there is a difference in SDD rates in those who receive TXA vs. those who do not. Secondary outcomes will assess bleeding complications (defined as unplanned ED visit/clinic visit/procedure/admission related to bleeding, clot retention, clot evacuation, need for perioperative transfusion) between participants who receive TXA vs. those do not. The study will also assess differences in perioperative complications associated with TXA including but not limited to: deep venous thrombosis, pulmonary embolism, cerebrovascular events, between the groups. The study will also assess for the duration of postoperative hematuria between groups as well as differences in operative times between the groups. The investigators anticipate that there may be up to a 25% increase in SDD rates in those who receive TXA vs. those who do not.

NCT ID: NCT05081960 Active, not recruiting - Kidney Stone Clinical Trials

Evaluating the Vitamin K2 Status of Calcium-based Stone Formers

Start date: August 1, 2022
Phase:
Study type: Observational

This is an observation, single site-study with one study visit during which all data and samples will be collected. Study participants will be asked to provide blood, urine, and fecal samples so that the investigators may study the differences in the gut microbiota, vitamin K2 levels, and other parameters between participants who form kidney stones and those who do not.

NCT ID: NCT05077007 Recruiting - Acute Kidney Injury Clinical Trials

Evaluation of Renal Damage After PCNL and ESWL Using Novel RNA Based Biomarkers

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The study evaluate the damage effect of ESWL and PCNL on kidney tissue by measuring non-coding lnc-RNA profile in urine before and after ESWL and PCNL procedures

NCT ID: NCT05068739 Completed - Biliary Stricture Clinical Trials

Needle Knife Fistulotomy Versus Partial Ampullary Endoscopic Mucosal Resection for Difficult Biliary Cannulation

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

The aims of this study are to compare the needle knife fistulotomy (NKF) technique versus the partial ampullary endoscopic mucosal resection (PA-EMR) technique in patients with difficult biliary cannulation and to assess the incidence rate of complications between these cannulation methods.

NCT ID: NCT05048706 Recruiting - Urinary Calculi Clinical Trials

SP TLF Versus Ho:YAG Laser

Start date: May 10, 2021
Phase: N/A
Study type: Interventional

The investigators aim to compare the performance of the Super Pulse Thulium fiber laser (SP TFL) with that of the standard Holmium: Yttrium-Aluminium-Garnet (Ho:YAG) laser. The investigators hypothesize that the electronically-modulated laser diodes, of the TFL offers the most comprehensive and flexible range of laser parameters among laser lithotripters leading to more efficient (4 times more) and effective stone dusting resulting in production of finer dust particles obviating the need for postoperative ureteric stenting which remains a major source of patient discomfort.

NCT ID: NCT05038540 Completed - Periodontitis Clinical Trials

The Effect of Virtual Reality Glasses on Dental Anxiety Control

Start date: October 8, 2021
Phase: N/A
Study type: Interventional

In this clinical study, it was aimed to evaluate whether there is a decrease in patient anxiety by applying virtual reality glasses, which are the product of new technology, during scaling and root planing treatment. Patients who required scaling and root planing treatment and also scored 9 or above according to the Dental Anxiety Scale were included in our study. Scaling and root planing was performed in a randomly selected intraoral quadrant of the patients, in the same way, with or without the use of virtual reality glasses. In the virtual reality glasses application, a video consisting of images of nature landscapes developed for patient rehabilitation was projected onto the screen in front of the patient's eyes. The Dental Anxiety Scale was reapplied after the completion of the treatment. In the intraoral quadrant where virtual reality glasses were used, it is expected that lower Corah Dental Anxiety Scale scores may be obtained after the treatment is completed, compared to the intraoral quadrant where the treatment is performed without glasses, thus reducing anxiety.

NCT ID: NCT05034705 Completed - Calculi Clinical Trials

A Randomised Controlled Clinical Trial on the Use of a Dental Aerosol Box to Prevent Microbial Transmission During Dental Procedure

Start date: September 6, 2021
Phase: N/A
Study type: Interventional

The study compares the use of a dental aerosol box in preventing microbial transmission during dental procedure. Subjects requiring scaling treatment (BPE 2) will be recruited. Subjects will be allocated either into the control group (conventional suction method) or interventional group (dental aerosol box) Treatment will involve scaling of two quadrants, where data collection of the microbes will be taken. Secondary outcome will involve a self-administered questionnaire on patients acceptance over the scaling procedure either with conventional suction or using the dental aerosol box to contain the aerosol generated during the scaling procedure.

NCT ID: NCT05027971 Completed - Clinical trials for Benign Prostatic Hyperplasia

Flexiva Pulse Registry

Start date: November 1, 2021
Phase:
Study type: Observational [Patient Registry]

To obtain post-market safety and efficacy data for FlexivaTM Pulse High Power Single-Use Laser Fibers during lithotripsy and soft tissue procedure of holmium laser enucleation of the prostate (HoLEP).

NCT ID: NCT05006937 Recruiting - Kidney Stone Clinical Trials

High Powered Stone Dusting vs. Fragmentation and Basketing at Time of Ureteroscopy

Start date: July 28, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the differences in stone free results, patient side effects, and patient satisfaction between dusting vs. basket extraction for kidney and ureteral stones (a kidney stone located in the tube between the kidney and bladder) 6 mm and greater in size undergoing ureteroscopic treatment. Dusting is when a laser is used to break a stone down into tiny fragments that are able to pass through the urine. Basket extraction is when a small wire basket is used to remove stone fragments.

NCT ID: NCT04980079 Recruiting - Ureter Obstruction Clinical Trials

Primary Versus Deferred Ureteroscopy for Calculus Anuria in Children

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

To evaluate the role of both primary and deferred URS in the management of calculus anuria concerning the feasibility, clinical outcome, and cost-effectiveness in children in a comparative study