Partners Calciphylaxis Biobank — PCB  

Chronic Kidney Diseases Clinical Trial

Official title: Partners Calciphylaxis Biobank and Patient Registry

Status Recruiting

Clinical Trial Summary

Calciphylaxis, a vascular calcification disorder, is a rare and serious disorder characterized by calcification of dermal arterioles.

There are significant gaps in the understanding of the pathophysiology and risk factors for calciphylaxis. At present, there is no effective treatment. Uncertain pathobiology, rare incidence and lack of collaborative approach have been some of the major limiting factors towards treating calciphylaxis.

The Partners Calciphylaxis Biorepository (PCB) aims to address these gaps within calciphylaxis research by utilizing existing and, when necessary, developing new infrastructure to support the consent of patients and the collection of dedicated samples for a calciphylaxis repository.

Clinical Trial Description

Calciphylaxis, a vascular calcification disorder, is a rare and serious disorder characterized by calcification of dermal arterioles.

There are significant gaps in the understanding of the pathophysiology and risk factors for calciphylaxis. At present, there is no effective treatment. Uncertain pathobiology, rare incidence and lack of collaborative approach have been some of the major limiting factors towards treating calciphylaxis.

The Partners Calciphylaxis Biorepository (PCB) aims to address these gaps within calciphylaxis research by utilizing existing and, when necessary, developing new infrastructure to support the consent of patients and the collection of dedicated samples for a calciphylaxis repository.

This repository is working in collaboration with the Partners Biobank as they will still be receiving samples from the PCB and storing them and distributing them according to their own procedures. ;

Related Conditions & MeSH terms

• Calcific Uremic Arteriolopathy
• Calciphylaxis
• Chronic Kidney Diseases
• End Stage Renal Disease
• Kidney Diseases
• Kidney Failure, Chronic
• Renal Insufficiency, Chronic

• NCT number: NCT03032835
• Study type: Observational [Patient Registry]
• Source: Massachusetts General Hospital
• Contact: Sagar U Nigwekar, MD, MMSc
• Phone: 617-726-7872
• Email: snigwekar@mgh.harvard.edu
• Status: Recruiting
• Start date: January 2017
• Completion date: December 2030