Caesarean Section Clinical Trial
Official title:
The Effects of Different Anesthetic Techniques on QT, Corrected QT (QTc), and P Wave Dispersions in Cesarean Section
Verified date | May 2017 |
Source | Trakya University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study evaluates the effects of different anesthetic techniques on QT, QTc, and Pwd in cesarean section. Half of participants received general anesthesia, while the other half received spinal anesthesia Electrocardiography (ECG) recordings were performed at preoperative, 5, 15, 30 min after initiation anesthesia and 30 min post-operatively. Hemodynamic state were also recorded at the same time intervals. QT, corrected QT (QTc), QT dispersion (QTd), QTc dispersion (QTcd), P-wave dispersion (Pwd), corrected JT interval, T wave (Tp-e), transmular dispersion of repolarization durations were measured from ECG records at predetermined time intervals of spinal or general anesthesia.
Status | Completed |
Enrollment | 90 |
Est. completion date | August 23, 2016 |
Est. primary completion date | July 23, 2016 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 20 Years to 40 Years |
Eligibility |
Inclusion Criteria: 1. American Society of Anesthesiologists physical status I-II 2. ages 20-40 years 3. parturient patients Exclusion Criteria: 1. spinal cord and peripheral nervous system diseases; 2. hypovolemic and hemorrhagic shock; 3. increased intracranial pressure; 4. severe anemia; 5. systemic infection; 6. scoliosis; 7. congenital spinal anomalies; 8. vertebral colon metastatic lesions; 9. anticoagulant drug use; 10. diabetes mellitus; 11. hypo/hyperthyroidism; 12. atrial and/or ventricular hypertrophy on ECG; 13. cardiomyopathy; 14. valvular disease; 15. cardiac failure or chronic disease; 16. cardiomegaly 17. used medication causing QT interval prolongation. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Trakya University |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Measurement of perioperative electrocardiogram changes | Electrocardiography measurements were performed and recorded for patients at preoperative, intraoperative 5th, 15th, 30th minutes and postoperative 30th minutes. Electrocardiogram is assessed change from Baseline at intraoperative and postoperative 30 min. Treatment-Related Adverse Events, cardiac disorder Assessed by CTCAE v4.0 | Preoperative, intraoperative and postoperative 30 min. |
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