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Development of a Non-invasive Assessment of Skeletal Muscle Loss in Cancer Patients

Cachexia Clinical Trial

Official title:
Development of a Non-invasive Assessment of Skeletal Muscle Loss in Cancer Patients

Clinical Trial Summary

The long-term objective of this research is to develop a non-invasive approach for early assessment of which patients are at high risk for future development of skeletal muscle atrophy. The investigators hypothesize that the rate constant for the terminal portion of the isotope decay curve following ingestion of a single oral dose of deuterated-3-methylhistidine (D-3MH) provides an accurate measure of this increased risk and that this rate constant can be measured non-invasively from timed spot urine samples. In addition, the investigators hypothesize that ingestion of a meat-containing meal will stimulate synthesis of skeletal muscle proteins to a greater extent than a non-meat-containing meal.

Clinical Trial Description

n/a

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00994669
Study type Observational
Source The University of Texas Medical Branch, Galveston
Contact
Status Completed
Phase N/A
Start date October 2009
Completion date October 2012
View Details
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