Child Development Clinical Trial
Official title:
Assessment and Management of Muscle Wasting in Children and Adolescents With Cancer
The series of the 3-year study aims to explore parents' experience of caring for a child's weight change among parents of children and adolescents with cancer, examine the associations and trends among muscle wasting and health-related variables, and then implement and assess effectiveness of a multidisciplinary approach with a personalized physical activity (walking) training intervention on improving muscle mass and other health-related variables.
Specific aims, year by year
1. The aim for Year 1 is as follows:
Aim 1: To explore parents' experience of caring for promoting a child's exercise among
parents of children and adolescents with cancer.
2. The aims for Year 2 are as follows:
Aim 2-1: To examine the associations between the degree of muscle wasting and
health-related variables (fatigue level, symptom distress level, physical activity
involvement, dietary intake, and QoL) among children and adolescents with cancer.
Aim 2-2: To examine the trends of changes in muscle wasting and health-related variables
(fatigue level, symptom distress level, physical activity involvement, dietary intake,
and QoL) during the first 6 months of cancer treatment among children and adolescents
with cancer.
3. The aim for Year 3 is as follows:
Aim 3: To examine the effectiveness of a multidisciplinary approach with a personalized
walking exercise program on changes in body composition and health-related variables (fatigue
level, symptom distress level, subjective physical activity involvement, objective physical
activity measurement, dietary intake, and QoL) among children and adolescents with cancer.
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