Response of Liver to 12 Weeks of Resistance Band Training Program in Burned Patients.

Burns Clinical Trial

Official title: Response of Liver Enzymes to 12 Weeks of Resistance Band Training Program in Burned Patients.

Status Recruiting

Clinical Trial Summary

Serum concentrations of alanine transaminase (ALT) and aspartate transaminase (AST) significantly increased immediately upon burn trauma and remained significantly elevated for about three years.

Resistance training has been shown to reduce the risk of insulin resistance, aminotransfer¬ase levels, dyslipidemia and impaired fasting glucose and can be beneficial for glucose-lipid metabolism.

Clinical Trial Description

1. Measurement procedures:

Serum blood draws will be taken by certified technicians with the participant in a seated position.

Spectrophotometry is the measurable analysis technique using electromagnetic spectra. It deals with the ranges of wavelengths such as near ultraviolet, near-infrared and visible light. A device called a spectrophotometer is used to measure the absorbance or transmittance through a liquid sample. The spectrophotometer measures a specific wavelength and it is possible to choose any wavelength in the spectrophotometer register as the double beam sends a beam through a blank reference sample and one through the sample to be measured.

Normal values that will be used for patients are 0-45 IU/l for Alanine transaminase (ALT) and 0-35 IU/l for Aspartate transaminase(AST) Measurements will be taken before the treatment (pre-treatment) and after 12 weeks (post-treatment).

2. Therapeutic procedures:

Resistance band for resistance training:

Resistance training will be performed for 12 weeks for 3 sessions/week on non-consecutive days. The program will consist of six exercises: triceps press, biceps curl, lat pull-down, leg press, leg extension and sit-ups using a resistance band. Each session will last approximately 45 minutes and consist of a 5-minute warm-up with stretching followed by resistance training that will be done as a cir¬cuit, ending with a 5-minute cooldown. The 1 repetition maximum (1RM) is measured at baseline and following the intervention. Initially, participants will do two circuits using 50% of their 1RM and repeat them 10 times for the first 3 weeks, progressing to two circuits, using 60% of their 1RM and repeating 10 times for the second 3 weeks. During the third 3 weeks, participants will do three circuits using 60% of their 1RM and repeat 10 times. In the last 3 weeks, patients will do three circuits using 70% of their 1RM and repeat 10 times. A 90-second rest will be allowed between sets of exercises. ;

Related Conditions & MeSH terms

• Burns

• NCT number: NCT06067711
• Study type: Interventional
• Source: Cairo University
• Contact: A G Elsayed, PHD
• Phone: 01001475959
• Email: drayasa3ada@yahoo.com
• Status: Recruiting
• Phase: N/A
• Start date: November 19, 2023
• Completion date: March 30, 2024