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Massive Burns: Retrospective Analysis of Changes in Outcomes Across 18 Years — MassiveBurns  

Burns Clinical Trial

Official title:
Massive Burns: Retrospective Analysis of Change in Outcomes Across 18 Years

Clinical Trial Summary

Burns treatment and management has evolved since the 90s, particularly for massive burns (≥ 50% of total body surface area (TBSA)). This study aims at analyzing the impact of the management changes on the length of intensive care unit (ICU) stay, the take of skin grafts and the mortality.

Clinical Trial Description

Review of all massively burned patients treated at Lausanne University Hospital burn intensive care unit (ca. 40-60 patients). Analysis of changes in length of intensive care unit stay (LICU), skin graft take rate or mortality between 2000 and 2018.

Hypothesis : the optimization of resuscitation procedures and of nutrition therapy combined with the use of novel surgical techniques has brought a significant improvement in outcomes.

Association between outcomes and year of admission will be assessed through correlation analysis and logistic regression analysis. Potential cofounders will be assessed through stepwise linear regression analysis ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04480944
Study type Observational
Source Centre Hospitalier Universitaire Vaudois
Contact
Status Completed
Phase
Start date January 1, 2019
Completion date March 31, 2020
View Details
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