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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03520816
Other study ID # 2016-12
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date October 1, 2016
Est. completion date April 1, 2017

Study information

Verified date May 2018
Source Hasan Kalyoncu University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Background: This study planned to investigate the effect of early physiotherapy on biochemical parameters in major burn patients.

Methods: Ten women (50%) and 10 men (50%) aged 21-47 years old were included in our study. Participants were divided into two groups: one group was the treatment group and the other was the control group. In the treatment group, patients were admitted to the physiotherapy programme from the first day they have been hospitalised, in addition to their routine treatment (medical, surgery, etc.), for 4 days per week. It consisted of parameters such as early mobilisation and ambulatory training, chest physiotherapy, and both active and passive normal joint movement exercises. The days of treatment were determined as Tuesday, Wednesday, Thursday and Friday. Patients could not be treated on a Monday because that was surgery day. The control group consisted of patients who could not receive physiotherapy due to various reasons. All patients included in the study were evaluated weekly for 6 weeks after admission to the hospital. Parameters such as demographic information, characteristics of burn injury, C-reactive protein, fibronectin, transferrin and prealbumin were evaluated.


Recruitment information / eligibility

Status Completed
Enrollment 20
Est. completion date April 1, 2017
Est. primary completion date February 1, 2017
Accepts healthy volunteers No
Gender All
Age group 21 Years to 47 Years
Eligibility Inclusion Criteria:

- Age = 18 years

- Major burn injury (according to ABA)

- Conscious patients

Exclusion Criteria:

- Inhalation injury

- Various chronic disorders

- Organ dysfunctions

Study Design


Related Conditions & MeSH terms


Intervention

Other:
Burn Physiotherapy Protocol
It consisted of parameters such as early mobilisation and ambulatory training, chest physiotherapy, and both active and passive normal joint movement exercises.

Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Hasan Kalyoncu University

References & Publications (5)

Chinese Burn Association; Chinese Association of Burn Surgeons, Cen Y, Chai J, Chen H, Chen J, Guo G, Han C, Hu D, Huan J, Huang X, Jia C, Li-Tsang CW, Li J, Li Z, Liu Q, Liu Y, Luo G, Lv G, Niu X, Peng D, Peng Y, Qi H, Qi S, Sheng Z, Tang D, Wang Y, Wu J — View Citation

Gillenwater J, Garner W. Acute Fluid Management of Large Burns: Pathophysiology, Monitoring, and Resuscitation. Clin Plast Surg. 2017 Jul;44(3):495-503. doi: 10.1016/j.cps.2017.02.008. Epub 2017 Apr 14. Review. — View Citation

Lee KC, Joory K, Moiemen NS. History of burns: The past, present and the future. Burns Trauma. 2014 Oct 25;2(4):169-80. doi: 10.4103/2321-3868.143620. eCollection 2014. — View Citation

Luzzani A, Polati E, Dorizzi R, Rungatscher A, Pavan R, Merlini A. Comparison of procalcitonin and C-reactive protein as markers of sepsis. Crit Care Med. 2003 Jun;31(6):1737-41. — View Citation

Mandell SP, Gibran NS. Early Enteral Nutrition for Burn Injury. Adv Wound Care (New Rochelle). 2014 Jan 1;3(1):64-70. Review. — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary Fibronectin Blood test Changes in fibronectin at 6 weeks later
Primary Prealbumin Blood test Changes in prealbumin at 6 weeks later
Primary C-reactive protein Blood test Changes in C-reactive protein at 6 weeks later
Primary Transferrin Blood test Changes in transferrin at 6 weeks later
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