Burns Clinical Trial - Catecholamine Blockade Post-burn

Status Active, not recruiting

Clinical Trial Summary

Severe burn is associated with a wide array of stress, metabolic, and physiologic processes in an attempt to restore homeostasis. The catecholamine induced stress response following severe burns is particularly exaggerated and manifests detrimentally as inflammation, insulin resistance, hypermetabolism, and associated profound protein catabolism. The investigators hypothesize that catecholamine blockade will lead to restored IR signaling and result in improved post-burn morbidity. The investigators will further determine the molecular mechanisms mediating these effects.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Burns

Clinical Trial Details

NCT number	NCT01299753
Study type	Interventional
Source	Sunnybrook Health Sciences Centre
Contact
Status	Active, not recruiting
Phase	N/A
Start date	February 2011
Completion date	December 31, 2023

View Details

See also
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