Clinical Trials Logo
  1. Home
  2. Burns
  3. NCT00609414
  4. Details
NCT00609414 Clinical Trial

Albumin Use in Burn Patients

Burns Clinical Trial

Official title:
Albumin Use in Burn Patients

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00609414
Other study ID # 04-1392
Secondary ID
Status Completed
Phase N/A
First received January 24, 2008
Last updated April 15, 2011
Start date January 2005
Est. completion date October 2008

Study information
Verified date April 2011
Source University of North Carolina, Chapel Hill
Contact n/a
Is FDA regulated No
Health authority United States: Institutional Review Board
Study type Observational

Clinical Trial Summary

This is a study of why and how physicians use albumin during the first 72 hours after a burn injury.

Description:

While albumin has been a part of burn resuscitation for many years, its use remains varied and controversial. The purpose of this study is to describe the current practices of albumin administration during the first 72 hours after a burn injury. Participating sites will collect data on patients with at least a 20% Total Body Surface Area (TBSA) burn. Information will be recorded on type and extent of burn injury, basic demographic data, co-morbidities, outcomes and, for the first 72 hours post injury, if albumin was used and why, amount of resuscitation fluids and urine output, and use of vasopressors and diuretics.

Each participating site will retrospectively review 20 charts of consecutive admissions with at least a 20% TBSA burn. In addition, each site will collect data prospectively on 20 more patients with 20% TBSA burns. Prospective data is requested in order to capture as close as possible to "real time" the reasons physicians choose to give albumin. No Protected Health Information (PHI) will be recorded.

Data will be analyzed for patterns of albumin use and reasons for albumin administration.

Recruitment information / eligibility
Status Completed
Enrollment 460
Est. completion date October 2008
Est. primary completion date October 2008
Accepts healthy volunteers No
Gender Both
Age group N/A and older
Eligibility Inclusion Criteria:

- Burn Injury, with and without inhalation injury

Exclusion Criteria:

- <20% Total Body Surface Area Burned

- Comfort care only for the burn injury

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Canada Ross Tilley Burn Centre, Sunnybrook Health Sciences Centre Toronto Ontario
United States Paul and Carol David Foundation Burn Institute, Akron Children's Hospital Akron Ohio
United States Joseph M Still Research Foundation Inc and Doctors Hospital of Augusta Augusta Georgia
United States North Carolina Jaycee Burn Center, University of North Carolina Hospitals Chapel Hill North Carolina
United States Shriners Hospitals for Children Cincinnati Ohio
United States Shands at the University of Florida Burn Center Gainesville Florida
United States Bothin Burn Center, University of Kansas Hospital Kansas City Kansas
United States Arizona Burn Center, Maricopa Medical Center Phoenix Arizona
United States Oregon Burn Center, Legacy Health System Portland Oregon
United States University of Utah Hospitals Burn Center Salt Lake City Utah
United States Bothin Burn Center, Saint Francis Memorial Hospital San Francisco California
United States Regions Hospital Burn Center St. Paul Minnesota

Sponsors (1)
Lead Sponsor Collaborator
University of North Carolina, Chapel Hill

Countries where clinical trial is conducted

United States,  Canada, 

See also
  Status Clinical Trial Phase
Completed NCT05023135 - DeepView SnapShot Portable (DV-SSP): Device Training Study
Completed NCT05276869 - Reliability and Feasibility of WeeFIM Instrument to Measure Functional Independence in Pediatric Burns
Completed NCT04548635 - VR for Burn Dressing Changes at Home Phase 2/Phase 3
Not yet recruiting NCT06076031 - Effects of Applying Streaming Media on Reducing Pain in Patient With Second-degree Burn During Changing Dressing N/A
Recruiting NCT05084248 - Vitamin D Deficiency in Adults Following a Major Burn Injury Phase 4
Completed NCT03113253 - TRANexamic Acid to Reduce Bleeding in BURN Surgery Phase 4
Recruiting NCT04090424 - Assessment of Safety and Effectiveness of NovoSorb® BTM in Severe Burns N/A
Not yet recruiting NCT05649891 - Checklists Resuscitation Emergency Department N/A
Withdrawn NCT03159182 - Study of Silicone Material Inserts To Treat Burn Scars N/A
Recruiting NCT02904941 - Human Amniotic Versus Synthetic Membrane as a Transient Skin Cover for Pediatric Burns N/A
Completed NCT02681757 - Comparison of Mepitel Ag vs Antibiotic Ointment Used With Soft Cast Technique for Treatment of Pediatric Burns N/A
Recruiting NCT01812941 - Evaluation of Mitochondrial Dysfunction in Severe Burn and Trauma Patients N/A
Completed NCT01437852 - StrataGraft® Skin Tissue as an Alternative to Autografting Deep Partial-Thickness Burns Phase 1
Completed NCT01214811 - Open Multi-centre Investigation to Evaluate Signs and Symptoms of Local Inflammation/Infection on Chronic Ulcers and Partial Thickness Burns When Using Mepilex Border Ag as an Anti-microbial Wound Dressing Phase 3
Completed NCT01061502 - Efficacy Study of a Bioelectric Dressing to Treat Skin Graft Donor Site Wounds Phase 1/Phase 2
Terminated NCT00822796 - Thermogard™ Efficacy Trial N/A
Terminated NCT00824681 - Effect of Music Therapy on Families of Burn Patients Phase 1
Terminated NCT00634166 - Effects of Therapy With Sulfamylon® 5% Topical Solution Compared to a Historical Control Group Phase 4
Terminated NCT00464386 - Continuous Glucose Monitoring (POC) in the ICU N/A
Withdrawn NCT00216983 - Proline Metabolism in Severely Burned Patients: Effect of Modulated Parenteral Feeding N/A