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Burns clinical trials

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NCT ID: NCT06163742 Not yet recruiting - Burns Clinical Trials

Novel Donor Site Dressing (Product X)

Start date: April 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test a novel donor site dressing called Product X in burn patients requiring skin grafting procedures. A donor site is an area where the surgeon has taken a layer of skin to create a graft. This is required to make severe burn wounds heal. However, donor sites often experience infection, pain, and itch that can delay the healing of the donor site. To prevent these complications, donor sites are covered with dressings to prevent infection and absorb fluids from the wounds. Many options exist, but no single dressing is best, especially for pain management and the ability to absorb fluids from wounds effectively. The investigators have developed a new donor site dressing to meet the criteria of an "ideal dressing," called Product X. The main question this clinical trial aims to determine the safety and potential wound-healing benefits of this donor site dressing as a new therapy that will help patients who require donor sites. Participants will: - Be randomized, like a flip of a coin, to receive either Product X or the standard-of-care dressings. If patients have one donor site, it will be randomized to receive either Product X or the standard-of-care dressings, Allevyn and Xeroform. If they have two donor sites, one donor site will be randomized to receive Product X and the other to receive standard-of-care dressings. - Have photographs of their donor sites taken at the operation, during dressing changes, at discharge, and at regularly scheduled outpatient follow-up appointments with the burn clinic. - Complete short questionnaires to assess their comfort (pain and itch) with their donor sites daily. - Complete a scar formation questionnaire at your regularly scheduled follow-up appointments in the outpatient burn clinic. Researchers will compare Product X to standard-of-care dressings (Allevyn and Xeroform) to see if there are improvements in wound healing, pain, itch, and infection.

NCT ID: NCT06162052 Recruiting - Burns Clinical Trials

Impact of a Telerehabilitation Program With Technology Enhancement on Post-burn Recovery

Start date: April 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the effect of participating in a tele-rehabilitation program after a burn.

NCT ID: NCT06160518 Completed - Burn Clinical Trials

Virtual Reality, Pain, Clinical Outcomes, Hydrotherapy, Children, Burn

Start date: July 27, 2023
Phase: N/A
Study type: Interventional

This study aims to evaluate the effect of virtual reality on pain and clinical outcomes during hydrotherapy for children with burn.

NCT ID: NCT06155149 Completed - Burns Clinical Trials

Effects of the Mobile Application Developed for Families After the Earthquake on First Aid Knowledge and Burn Prevention

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

The aim of this project was to determine the effect of the burn prevention and first aid mobile application developed for families living in tent cities and container houses after the earthquake on the burn prevention and first aid knowledge of families and the development of burns in the first two months after the mobile application. The research was planned as a prospective, two-arm (1:1), randomized controlled trial. The study population will consist of families living in tent cities and container houses in Şanlıurfa. As a result of the power analysis performed in the G*Power program, the sample group will consist of 30 families from the tent city and 30 families from the container city, taking into account the losses with a power of 90% and a maximum bidirectional 5% type error. All of the families (30 mobile application-study group; 30 control group) who make up the sample of the research will be given a training (powerpoint presentation) prepared by the researcher in line with the literature, and burn prevention and first aid practices will be explained and their questions will be answered. Then, the training to be given with the mobile application will be downloaded to the phones of the families in the experimental group and the training will continue through the application. In the study, data will be collected with the "Descriptive Characteristics Form", "Information Form on Burn Prevention and First Aid" and "Burn Development Follow-up Form", which include the descriptive information of the families. The data obtained from the study will be analyzed in computer environment.

NCT ID: NCT06143683 Not yet recruiting - Burns Clinical Trials

Early Versus Late Upper Extremity Mobilization After Meshed / Sheet Split Thickness Skin Autograft on Wound Healing in Adult Burn Patients

EXTREMA
Start date: January 2024
Phase: N/A
Study type: Interventional

STSGs are used to close wounds and minimize infections. After receiving a meshed or sheet split-thickness skin graft (STSG) to the upper extremity or hand for a thermal burn injury, burn surgeons use different methods to improve graft take and reduce complications. This includes different start dates and times for activity. The goal of this clinical trial is to provide more evidence to improve rehabilitation procedures after STSG operations for patients with burn injuries. The main question[s] it aims to answer are: - To determine if early mobilization is non-inferior to late mobilization of the upper extremity after meshed STSG with regards to wound healing in adult burn patients. - To determine if early mobilization is non-inferior to late mobilization of the upper extremity after sheet STSG with regards to wound healing in adult burn patients Participants will be assigned randomly (like flipping a coin) to one of two groups: early mobilization and late mobilization. Mobilization is the range of motion exercises performed under the supervision of the physical therapy team. Researchers will compare early and late mobilization to see if there are differences in wound healing, range of motion, local and systemic complications, and discharge outcomes. Participants will be asked to: - Early mobilization group: begin mobilization of their upper extremity one day after their STSG operation. If their burn includes a graft to your hand, early mobilization of this area will begin three days after their STSG operation. - Late mobilization group: elevate their elbow in a splint to limit movement until five days after their operation and begin mobilization five days after their STSG operation.

NCT ID: NCT06142591 Completed - Burns Clinical Trials

Oxycodone (10, 20 mg) in a Postoperative Dressing

Start date: January 1, 2016
Phase: Phase 4
Study type: Interventional

The study mainly focuses on pain management using 10- or 20mg oxycodone burn wound dressing at Poznan University of Medical Sciences.

NCT ID: NCT06138886 Recruiting - Burns Clinical Trials

Calisthenics Exercise and Electromagnetic Therapy on Liver Function Following Burn Injuries.

Start date: November 14, 2023
Phase: N/A
Study type: Interventional

Serum concentrations of alanine transaminase (ALT) and aspartate transaminase (AST) significantly increased immediately upon burn trauma and remained significantly elevated for about three years. Calisthenics exercises consist of movements that increase the flexibility and strength of the body. It is a type of exercise consisting of various movements applied without equipment and apparatus, using your body weight. Clinical evidence shows that PEMF therapy reduces pain associated with trauma from accidents, sports injuries, surgeries and burns as well as from disease and degeneration. PEMF therapy improves these conditions in many different concurrent ways including mechanical, chemical, electrical and magnetic processes within the cells of the body.

NCT ID: NCT06131203 Recruiting - Burns Clinical Trials

Burn Pivotal Study

Start date: December 19, 2023
Phase:
Study type: Observational

The purpose of this study is to validate the algorithm for burn healing assessment by the Spectral MD DeepView device which would provide burn healing potential assessment.

NCT ID: NCT06126991 Recruiting - Burns Clinical Trials

Organ Protective Effect of Cetirizine In Patients With Severe Burns

Start date: January 23, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

This prospective clinical trial aims to investigate the organ protective effects of cetirizine in patients with severe burns.

NCT ID: NCT06122532 Not yet recruiting - Large Area Burns Clinical Trials

Umbilical Cord Mesenchymal Stem Cells for the Repair of Large Area Burn Wounds

Start date: December 20, 2023
Phase: N/A
Study type: Interventional

This study intends to adopt a prospective, open, and randomized controlled research method to explore the effectiveness and safety of using human umbilical cord mesenchymal stem cells to treat large-scale burn wounds, in order to break through the limitations of various current treatment methods, explore new clinical treatment methods, promote the repair and healing of skin lesions, and further improve the cure rate and quality of life of patients.