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Burns clinical trials

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NCT ID: NCT06174155 Recruiting - Clinical trials for Hand-burned Children

Comparative Study Between Botulinum Toxin-A Injection and Shock Waves on Hypertrophic Scars in Hand-burned Children

Start date: December 15, 2023
Phase: N/A
Study type: Interventional

PURPOSE: The study aims to compare study between Botulinum toxin-A injection and shock waves therapy on hypertrophic scars in hand-burned children. BACKGROUND: Burn injuries can cause significant physical and psychological distress, especially when they result in hypertrophic scarring. In children, who are particularly vulnerable to these injuries, it is important to accurately assess the severity of these scars and their impact on functionality. HYPOTHESES: There is no significant difference between the combined effect of the traditional physical therapy program with botulinum toxin-A injection and the traditional physical therapy program with shock waves therapy on improving wrist extension, ulnar deviation, radial deviation, hand grip strength, and severity of the scar on hypertrophic scars in hand-burned children.

NCT ID: NCT06162052 Recruiting - Burns Clinical Trials

Impact of a Telerehabilitation Program With Technology Enhancement on Post-burn Recovery

Start date: April 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the effect of participating in a tele-rehabilitation program after a burn.

NCT ID: NCT06138886 Recruiting - Burns Clinical Trials

Calisthenics Exercise and Electromagnetic Therapy on Liver Function Following Burn Injuries.

Start date: November 14, 2023
Phase: N/A
Study type: Interventional

Serum concentrations of alanine transaminase (ALT) and aspartate transaminase (AST) significantly increased immediately upon burn trauma and remained significantly elevated for about three years. Calisthenics exercises consist of movements that increase the flexibility and strength of the body. It is a type of exercise consisting of various movements applied without equipment and apparatus, using your body weight. Clinical evidence shows that PEMF therapy reduces pain associated with trauma from accidents, sports injuries, surgeries and burns as well as from disease and degeneration. PEMF therapy improves these conditions in many different concurrent ways including mechanical, chemical, electrical and magnetic processes within the cells of the body.

NCT ID: NCT06131203 Recruiting - Burns Clinical Trials

Burn Pivotal Study

Start date: December 19, 2023
Phase:
Study type: Observational

The purpose of this study is to validate the algorithm for burn healing assessment by the Spectral MD DeepView device which would provide burn healing potential assessment.

NCT ID: NCT06126991 Recruiting - Burns Clinical Trials

Organ Protective Effect of Cetirizine In Patients With Severe Burns

Start date: January 23, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

This prospective clinical trial aims to investigate the organ protective effects of cetirizine in patients with severe burns.

NCT ID: NCT06122090 Recruiting - Cicatrix Clinical Trials

Treatment of Hypopigmented Scars With Bimatoprost

Start date: July 18, 2023
Phase: Phase 2
Study type: Interventional

Patients who have hypo-pigmented burn scar will have two scars chosen and randomized to treated scar and control scar. The subject will then have both scars treated with fractional ablative CO2 laser (FLSR). The treated scar will have bimatoprost delivered through the laser channels, while the control will have the vehicle (normal saline) only delivered. The treatment will continue for 14 days with twice daily application. The scars will then be monitored at a 2-week follow-up visit where levels of melanin will be evaluated. Tissue punch biopsies will also be used to evaluate the mechanism of action of bimatoprost. Treatment will occur for 6 sessions at 4-6 week intervals including follow- up visits and evaluations.

NCT ID: NCT06116227 Recruiting - Burns Clinical Trials

Whole-Body Vibration Training On Thermal Burn Injury In Pediatrics

Start date: October 30, 2023
Phase: N/A
Study type: Interventional

60 Patients with partial and full thickness thermal burns of the lower limb and trunk will be indiscriminately assigned to study group Group A(Study group): 30 patients received whole body vibration training on a vibration platform 12-15 minutes, 5 times per week, plus traditional physical therapy exercise program in the form of 60 minutes supervised exercise program for 8 weeks. Group B (control group):30 patients will receive a traditional physical therapy program. The program consists of 60 minutes of supervised stretching exercise to all involved joints followed by strengthening for affected muscles for 8 weeks.

NCT ID: NCT06104540 Recruiting - Itching Clinical Trials

Comparison of the Effects of Liquid Vaseline and Olive Oil on Itching and Scarring in Scald Burns

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

Pain, itching, hypertrophic scar formation after wound healing in burn patients complications, sleep disturbances in patients, anxiety, depression, and daily life It may disrupt activities and deterioration in quality of life. Liquid petroleum jelly and olive oil have no side effects, moisturizing properties, or wound-healing treatment of burns due to their positive effects on symptoms such as itching. can be used to alleviate burns. The project found the use of liquid petroleum jelly and olive oil to determine the effect on itching and scarring in burn patients. After burns reduction of symptoms such as itching, dryness, hypertrophic scarring, and patient comfort. Provision of care is a part of nursing care. In studies, itching and scarring there is insufficient evidence regarding the treatment methods applied for its treatment is observed. In addition, the effect of olive oil and liquid petroleum jelly on itching and scarring no scientific study was found. The results of the project were found to be significant in terms of post-burn itching providing evidence of hypertrophic scar management and contributing to ongoing studies is expected to be found. Since there are no similar studies in the literature, a preliminary study with 24 patient applications will be made. In line with the data obtained from the pre-application, the sample calculation will be made and the application will continue by making the necessary arrangements. Patients will be divided into experimental and control groups by simple randomization. All patient groups individual data collection forms on the first day; 12 individual data collection forms on the first day, 15th day, first, second, and third months Itemized Itch Severity Scale, Patient and Observer Scar Scale to be applied in Burn Patients and the wound area will be photographed. Patients in the control group will be given no application will be made. Liquid petroleum jelly and olive oil group before the study training will be given and they will massage the recommended product twice a day for 3 months and will be asked to record them. The data obtained at the end of the project will be statistically analyzed and results will be presented.

NCT ID: NCT06081504 Recruiting - Burns Clinical Trials

Wii Fit Exercises Versus Pilates Exercises in Adult Patients With Lower Extremity Burn

Start date: October 10, 2023
Phase: N/A
Study type: Interventional

The aim of the study is to compare the effect of Wii fit exercises and Pilates exercises on muscle strength and postural balance, and functional performance in adult patients with lower extremity burn.

NCT ID: NCT06067711 Recruiting - Burns Clinical Trials

Response of Liver to 12 Weeks of Resistance Band Training Program in Burned Patients.

Start date: November 19, 2023
Phase: N/A
Study type: Interventional

Serum concentrations of alanine transaminase (ALT) and aspartate transaminase (AST) significantly increased immediately upon burn trauma and remained significantly elevated for about three years. Resistance training has been shown to reduce the risk of insulin resistance, aminotransfer¬ase levels, dyslipidemia and impaired fasting glucose and can be beneficial for glucose-lipid metabolism.