Burns Degree Second Clinical Trial
Official title:
Use of Platelet-Rich Plasma in Second-Degree Superficial Burns; Multicentric Prospective Randomized Study
Verified date | October 2020 |
Source | Konya Training and Research Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Platelet-rich plasma (PRP) obtained from the patient's blood has been used in many clinical and experimental studies, primarily wound healing, and successful results have been achieved. PRP has been used in various studies in the treatment of burn wounds, and positive results have been obtained. However, investigators did not find any study or publication about the use of PRP in second-degree superficial burns in our screening. Investigators planned a prospective randomized controlled and multicenter study to investigate the positive effects of PRP in the treatment of second-degree superficial burn.
Status | Completed |
Enrollment | 62 |
Est. completion date | October 23, 2020 |
Est. primary completion date | September 30, 2020 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 16 Years to 90 Years |
Eligibility | Inclusion Criteria: - having a second-degree superficial burn - To be over the age of 16. Exclusion Criteria: - Patients under 16 - Patients with a burn of more than 30% of the total body surface area. - Patients with additional trauma with a burn wound. - Diabetes mellitus, renal failure requiring dialysis and having decompensated heart disease - Being pregnant and breastfeeding. - The patient does not want to participate in the study. |
Country | Name | City | State |
---|---|---|---|
Turkey | Konya Training and Research Hospital | Konya |
Lead Sponsor | Collaborator |
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Konya Training and Research Hospital |
Turkey,
Grippaudo FR, Carini L, Baldini R. Procutase versus 1% silver sulphadiazine in the treatment of minor burns. Burns. 2010 Sep;36(6):871-5. doi: 10.1016/j.burns.2009.10.021. Epub 2010 Jan 15. — View Citation
Venter NG, Marques RG, Santos JS, Monte-Alto-Costa A. Use of platelet-rich plasma in deep second- and third-degree burns. Burns. 2016 Jun;42(4):807-14. doi: 10.1016/j.burns.2016.01.002. Epub 2016 Jan 25. — View Citation
Zheng W, Zhao DL, Zhao YQ, Li ZY. Effectiveness of platelet rich plasma in burn wound healing: a systematic review and meta-analysis. J Dermatolog Treat. 2020 Feb 21:1-7. doi: 10.1080/09546634.2020.1729949. [Epub ahead of print] — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | PRP use in second degree burn treatment | In the study, the effectiveness of burn treatment in both groups will be determined by recording the day of epithelialization. | 01.03.2020-30.04.2020 |
Status | Clinical Trial | Phase | |
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Recruiting |
NCT05347654 -
Evaluation of a Management Strategy for Second-degree Fibrinous Burns Integrating a Poly-absorbent Dressing
|
N/A |