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Clinical Trial Summary

By doing this study, researchers hope to learn if applying Santyl to the burn during the healing process affects the appearance of the resulting scar.


Clinical Trial Description

Subjects who have minor, second degree burns may be enrolled in this study. Subjects will receive either Santyl ointment or bacitracin ointment to apply to the burn until it heals. Bandages will be used to keep the burn covered while it heals. Second degree burns generally leave a scar. Once the burn heals, lotion and an appropriate bandage will be used to try to minimize the appearance of a scar.

The study hypothesis is that burns treated with Santyl will have a better scar appearance than burns treated with bacitracin.

Subjects enrolled in this study will make once a week visits to the University of Kansas Medical Center outpatient burn clinic until the burn heals. The burn will be assessed for healing at these visits. Once healed, visits to the clinic will be at 60 & 180 days, up to 6 months. At these visits, the appearance of the scar will be evaluated.

This study was originally funded by Smith and Nephew, but Smith and Nephew is no longer providing support for the study. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02673229
Study type Interventional
Source University of Kansas Medical Center
Contact Jessica Reynolds, BSN
Phone 913-588-0044
Email jreynolds11@kumc.edu
Status Recruiting
Phase Phase 4
Start date January 2014
Completion date December 2021

See also
  Status Clinical Trial Phase
Withdrawn NCT01516463 - Using Santyl or Bacitracin on Second Degree Burns Phase 4
Completed NCT04079998 - Procellera® Compared to Standard of Care Treatment in Mitigating Biofilm Formation in Acute Trauma and Burn Wounds N/A
Completed NCT05148390 - Study to Examine Clinical Performance and Safety of Cutimed® Gelling Fiber in Routine Clinical Practice