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Burn Injury clinical trials

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NCT ID: NCT04417439 Completed - Burn Injury Clinical Trials

The Effect of Acute Phase Treatment Approaches on Creatine Kinase and the Musculoskeletal System in Different Types of Burns

Start date: May 12, 2018
Phase:
Study type: Observational

There are very few studies indicating the effect of acute phase treatment approaches on creatine kinase and the musculoskeletal system in the physiotherapy and rehabilitation process. Rehabilitation in burn patients is a benchmark due to return to pre-burn life. Therefore, this study was conducted to determine the effect of acute phase treatment approaches on creatine kinase and the musculoskeletal system in different types of burns.

NCT ID: NCT04368117 Recruiting - Burn Injury Clinical Trials

STAT: Standard Therapy Plus Active Therapy

STAT
Start date: October 26, 2020
Phase: N/A
Study type: Interventional

The objective of the study is to assess the efficacy of STAT, an activity-based therapy protocol compared to standard therapy (ST) to improve functional outcome and reduce disability in patients recovering from burn injury. This randomized multi-center trial is designed with two parallel treatment groups: STAT and ST. Efficacy of the STAT protocol will be determined through comparison to the ST only group. It will be conducted at seven burn centers.

NCT ID: NCT04356859 Recruiting - Burn Injury Clinical Trials

The Acute Burn ResUscitation Multicenter Prospective Trial

ABRUPT2
Start date: April 22, 2021
Phase: N/A
Study type: Interventional

This is a prospective randomized multi-center study which will compare acute fluid resuscitation using a colloid strategy (LR + 5% Albumin) to a crystalloid strategy (LR alone), in adults with an acute burn involving at least 25% of their total body surface area.

NCT ID: NCT03906721 Completed - Clinical trials for Spinal Cord Injuries

Reduction of Opioid Dose Using Conditioning & Open-Label Placebo (COLP) in Patients With Spinal Cord Injury, Polytrauma and Burn Injury

Start date: February 20, 2019
Phase: Phase 2
Study type: Interventional

The use of conditioning open-label placebo (COLP) will be studied as a dose extension method to lower opioid dosage in patients with spinal cord injury, polytrauma, and burn injury. The goal is to provide the same level of pain relief with a reduced opioid dose to diminish adverse effects as well as the risk of addiction associated with narcotic treatment.

NCT ID: NCT03759613 Completed - Burn Injury Clinical Trials

Evaluation of Gait Symmetry in Upper Extremity Burn Injuries

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

Thirty patients with unilateral burn injury, and 60 healthy subjects will be included in this study. Participants with burn injury will evaluate with the following assessment tools: Demographic data; age, gender, height, body mass index; burn characteristics; type of burn injury, degree of burn injury, localization of burn injury and total burn surface area will be recorded. Gait parameters (step length, stride length, base support, step time, cycle time, cadence, velocity, single support, double support, swing ( % of gait cycle) and stance (% of gait cycle). will be recorded via computerized system. And gait symmetry will be calculated via formule. Participants' kinesiophobia level will be evaluated with Tampa kinesiophobia scale. Their pain will be assessed by visual analog scale. Their arm swing will be evaluated by a scale.

NCT ID: NCT03730688 Completed - Burn Injury Clinical Trials

Non-invasive Limb Compartment Pressure Measurement

FNO-TRAUMA-CPM
Start date: September 1, 2018
Phase: N/A
Study type: Interventional

Compartment syndrome (CS) is a serious complication of soft-tissue injuries in patients with fractures of the musculoskeletal apparatus. CS is defined as a condition, during which an increased tissue pressure inside an enclosed compartment damages the microcirculation and neuromuscular function of the tissue, and results in ischemization, with a damage of nerve-muscle structures, which lead either to extensive flexion contractures, or myonecroses, with the need to perform an early amputation of the affected limb. In traumatology, compartment syndrome is most frequently observed in a patient with crural fractures, closed as well as open fractures, or in cases of crus laceration.

NCT ID: NCT03618940 Recruiting - Burn Injury Clinical Trials

Module on Preventing Fire, Burns and Scalds Injury Among Children

Start date: January 1, 2016
Phase: N/A
Study type: Interventional

The main aim of this intervention study is to test the hypothesis if school based educational intervention program will significantly improve the knowledge of primary school student on childhood burn prevention in Kuala Lumpur. The secondary aim the evaluate the association of demographics background, burn injury history with knowledge on burn. The study was conducted in 12 primary school in Kuala Lumpur from 1st January 2015 to 31st December 2017 in three different phases.

NCT ID: NCT03343353 Not yet recruiting - Burn Injury Clinical Trials

Therapy by Led (Light Emission Diode) in Cutaneous Lesion: in Vivo

Start date: February 19, 2018
Phase: N/A
Study type: Interventional

Light Emitting Diode (LED) therapy has been investigated in burns and skin ulcers, as it has a bactericidal effect and promotes tissue repair. This study aims to evaluate LED therapy at different wavelengths in the healing process of graft donor area in adult burn victims.

NCT ID: NCT03204669 Completed - Critical Illness Clinical Trials

Trace Element Repletion Following Severe Burn Injury

Start date: June 1, 1999
Phase: N/A
Study type: Observational

Major burn patients are characterized by large exudative losses of Cu, Se and Zn. Trace element (TE) repletion has been shown to improve clinical outcome. The study aimed to check if our repletion protocols were achieving normalization of TE plasma concentrations of major burn patients and if the necessity for continuous renal replacement therapy (CRRT) might increase the needs.

NCT ID: NCT02619851 Completed - Burn Injury Clinical Trials

A Clinical Trial to Evaluate the Safety and Efficacy of ALLO-ASC-DFU for Second Deep Degree Burn Injury Subjects

Start date: December 23, 2015
Phase: Phase 2
Study type: Interventional

This clinical trial is a Phase II controlled, parallel, open-label trial, designed to test the efficacy and safety of ALLO-ASC-DFU and conventional therapy in Deep Second-degree burn wound subjects.