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Bunion clinical trials

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NCT ID: NCT04398329 Completed - Bunions Clinical Trials

Dose-Escalation Study of HTX-034 Following Bunionectomy

Start date: May 18, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

This is a Phase 1b/2, randomized, blinded, active-controlled study. Phase 1b will evaluate escalating doses of HTX-034 compared with bupivacaine HCl. Phase 2 will be a dose-expansion phase to evaluate additional subjects treated with the HTX-034 dose selected based on Phase 1b compared with bupivacaine HCl.

NCT ID: NCT04393545 Completed - Hallux Valgus Clinical Trials

Efficacy of Splinting, Exercise and Electrotherapy on Hallux Valgus

Start date: February 2, 2009
Phase: N/A
Study type: Interventional

The aim of this study was to investigate the effects of splinting, exercise and electrotherapy on the hallux valgus (HV) angle, and foot-specific health-related quality of life. Sixty women (120 feet) with bilateral HV deformity were randomly assigned to one of three groups - an HV night splint (SP) group, an exercise (EX) group, and a high-voltage galvanic stimulation (EL) group. Angular degrees (hallux interphalangeal, HV, and intermetatarsal angles expressed as angles A, B and C, respectively) were determined before enrollment (t0) and three months after treatment (t2). Foot-specific quality of life was assessed using the Manchester-Oxford Foot Questionnaire (MOFQ) at t0, after one month (t1), and at t2. All groups exhibited significant changes in the A, B, and C angles and outcome measures (p ≤0.001). Decreases in the A and C angles, and MOFQ-Pain subscale scores, were higher in the SP group than in the other two groups (p<0.05). C angle at t2, MOFQ-Walking score at t1 and t2 and MOFQ-Pain subscale score at t1 were lower in the SP group (p<0.05).

NCT ID: NCT04365712 Completed - Hallux Valgus Clinical Trials

Osteotomy of the 1st Metatarsal for Hallux Valgus Using Pneumatic Oscillating Saw or Piezoelectric Scalpel

Piezo-Hallux
Start date: October 24, 2014
Phase: N/A
Study type: Interventional

The main goal of the surgical correction of the hallux valgus is the morphological correction associated with the functional rebalancing of the first ray. The aim of this study was to show the efficacy of piezosurgery in performing distal linear osteotomy of the first metatarsal bone in hallux valgus correction, in terms of clinical and radiological outcomes at 1-year final follow up.

NCT ID: NCT04284618 Completed - Hallux Valgus Clinical Trials

Off Axis View Radiographs Assessing Hallux Valgus Interphalangeus in Hallux Valgus Deformity

Start date: November 10, 2018
Phase:
Study type: Observational

In hallux valgus deformity an additional deformity of the proximal phalangeal bone can be observed frequently as well. Due to a hyperpronation of the greater toe on standardized radiographs the deformity defining angles are likely to be underestimated. Therefore the investigators developed an off axis view radiograph for determining the real deformity. This study compares the standardized and the off axis view radiographs.

NCT ID: NCT04088214 Completed - Hallux Valgus Clinical Trials

Arthroscopic Assisted Lateral Soft Tissue Release for Hallux Valgus

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

Lateral soft tissue release is commonly performed as part of the surgical correction of hallux valgus. This study will look at the results form a series of patients whom have underwent the arthroscopic lateral soft tissue release.

NCT ID: NCT04084262 Completed - Hallux Valgus Clinical Trials

Multi-Plane Hallux Valgus Correction With the Phantom® Nail

Start date: November 7, 2019
Phase:
Study type: Observational

The goal of this research study is to determine the change in frontal plane rotation of the 1st metatarsal from pre to post arthrodesis of the 1st TMT joint with the Phantom® Intramedullary Nail combined with a supinating reduction technique. The study hypothesis is that multi-planar correction can be achieved with the Phantom® Intramedullary Nail.

NCT ID: NCT04002089 Completed - Bunion Clinical Trials

Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety, of EXPAREL Administered as Sciatic Nerve Block (In Popliteal Fossa), for Postsurgical Analgesia in Subjects Undergoing Bunionectomy

Start date: July 26, 2019
Phase: Phase 1
Study type: Interventional

This is a pilot, open label, single center study in 40 subjects undergoing bunionectomy. The study will assess and collect information on pharmacokinetics, pharmacodynamics, safety and efficacy of EXPAREL administered as a sciatic nerve block (in popliteal fossa). A total of 10 subjects will be enrolled in each of the 4 cohorts.

NCT ID: NCT03846687 Completed - Hallux Valgus Clinical Trials

Validation of Patient Reported Outcome Measures for Use in Hallux Valgus

Start date: October 30, 2018
Phase:
Study type: Observational

The purpose of the study is to explore whether the mFFI is fit for purpose in adults with hallux valgus (HV).

NCT ID: NCT03815422 Completed - Clinical trials for Hallux Valgus Ambulatory Surgery

Plantar Compartment Block in Hallux Valgus Ambulatory Surgery

Observationnal
Start date: December 1, 2017
Phase:
Study type: Observational

Hallux valgus surgery is known as a painful surgery. Qualitative pain management is the key to successful early recovery and rehabilitation. Popliteal sciatic nerve block is widely used despite the risk of falling due to prolonged motor blockade. Plantar block combined with distal peroneal block may be a better analgesic option in order to provide fast track rehabilitation. The purpose of this study is to describe the analgesic effect of the plantar compartment block following hallux valgus surgery.

NCT ID: NCT03669900 Completed - Hallux Valgus Clinical Trials

Outcomes of Hallux Valgus Correction Surgery

Start date: March 10, 2018
Phase: N/A
Study type: Interventional

HV correction surgery using SERI appear to sufficiently reduce the severity of HV deformity in all radiological measurements (HVA, IMA, DMAA) and the correction of subluxation of the first MTP joint and the sesamoids. SERI technique is an easy, inexpensive, less invasive, more cosmetic, with shorter operative time and with minimal complication rates. To our knowledge, there is no report regarding HV treatment using SERI from Saudi Arabia or in any part of the Middle East. Therefore, this study conducted to determine the radiological measurements done preoperatively and compare the measurements done at one year postoperatively, recording the complication happened and measuring the cost effectiveness of such procedure.