Bulimia Nervosa Clinical Trial
Official title:
Targeting Inhibitory Control Using Computerised Training Among Patients With Bulimia Nervosa and Binge Eating Disorder
This research project aims to explore the feasibility of a computerised training to reduce
approach to high energy-dense foods among individuals who binge eat. The computerised
intervention used will be an inhibitory control training, particularly, a food-specific
go/no-go task. Eighty adults with a diagnosis of bulimia nervosa or binge eating disorder who
are currently receiving psychological and/or pharmacological treatment for their eating
disorder will be recruited and randomised to receive the computerised training in addition to
treatment as usual (experimental group: training + TAU) or treatment as usual only (control
group: TAU). Participants will complete questionnaires at baseline (T0), post-intervention
(T1; 4 weeks), and follow-up (T2; 8 weeks).
Participants will be asked to complete the computerised training for 4 weeks using a mobile
app called FoodT. The computerised training consists of completing a food-specific go/no-go
task to reduce approach to high energy-dense foods.
The results of this study will build steps for future larger-scale interventions and improve
understanding of psychological mechanisms involved in binge eating behaviour.
Participants will learn about the study through flyers, e-mail, and social media (i.e.
Facebook and twitter), which will describe the main eligibility criteria and the researcher's
contact information. Participants will also learn about the study from their eating disorder
unit if they are currently outpatients at one of the identification centres. Inpatients will
not be recruited.
Interested individuals will be asked to contact the researchers, who will then send an
information sheet detailing the study procedure and what participation would involve. After
reading the information sheet, interested individuals will be contacted by the researchers in
order to confirm all eligibility criteria including diagnostic assessment. If these are met,
a PDF of the consent form will be sent to the participants, including information about their
rights as participants and their ability to withdraw at any time without having to give a
reason. Participants who sign the consent form will respond to the e-mail with the attached
document. Next, participants will be randomly allocated to the experimental condition (TAU +
training) or control group (TAU only). Researchers will then inform the participant which
group they have been allocated to. If they are in the intervention group, the researcher will
contact the participant to give details about the training. All participants will be asked to
complete a battery of questionnaires on Qualtrics, an online platform.
The questionnaires will collect data regarding: 1) a demographic information, 2) eating
disorder symptoms (Eating Disorders Examination Questionnaire; Self-Regulation of Eating
Behaviour Questionnaire; Adult Eating Behaviour Questionnaire; Yale Food Addiction Scale;
Food Liking Task), 3) impulsivity (Negative Urgency Scale), 4) symptoms of anxiety or
depression (GAD-7 anxiety; PHQ-9 Depression) and 5) quality of life (EQ-5D-3L).
Participants in the intervention group will be asked to complete the training and a food
diary for four weeks. After the four weeks, all participants will be asked to complete the
same battery of questionnaires (except for the demographic questionnaire). One month
post-intervention, a follow-up questionnaire will also be sent.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Enrolling by invitation |
NCT04174703 -
Preparing for Eating Disorders Treatment Through Compassionate Letter-Writing
|
N/A | |
| Terminated |
NCT04278755 -
Binge Eating & Birth Control
|
Phase 2 | |
| Withdrawn |
NCT02978742 -
Evaluating and Implementing a Smartphone Application Treatment Program for Bulimia Nervosa and Binge Eating Disorder
|
N/A | |
| Withdrawn |
NCT00988481 -
Topiramate Augmentation in Bulimia Nervosa Partial Responders
|
Phase 4 | |
| Completed |
NCT00184301 -
A Comparison Study of Treatments Given to Patients With Concurrent Eating Disorder and Personality Disorder.
|
N/A | |
| Completed |
NCT00522769 -
Cognitive Behavioral Therapy to Treat Bulimia Nervosa in Adolescents
|
Phase 1/Phase 2 | |
| Completed |
NCT00304187 -
Effectiveness of Antibiotic Treatment for Reducing Binge Eating and Improving Digestive Function in Bulimia Nervosa
|
Phase 2 | |
| Recruiting |
NCT04409457 -
Self-Control in Bulimia Nervosa
|
N/A | |
| Recruiting |
NCT05509257 -
Naltrexone Neuroimaging in Teens With Eating Disorders
|
Early Phase 1 | |
| Recruiting |
NCT05937243 -
Identifying Effective Technological-based Augmentations to Enhance Outcomes From Self-help Cognitive Behavior Therapy for Binge Eating
|
N/A | |
| Recruiting |
NCT05862389 -
Study on the Mechanism of Eating Disorder
|
||
| Recruiting |
NCT05728021 -
Smartphone-based Aftercare for Inpatients With Bulimia Nervosa
|
N/A | |
| Completed |
NCT03781921 -
The Neural Bases of Emotion Regulation in Bulimia Nervosa
|
||
| Completed |
NCT02553824 -
FDA Approved Medication to Reduce Binge Eating and/or Purging
|
Phase 1 | |
| Terminated |
NCT04041024 -
Decision-making and Risk-taking in Bulimia
|
N/A | |
| Completed |
NCT04265131 -
Emotion Regulation in Eating Disorders: How Can Art Therapy Contribute to Treatment Outcome?
|
N/A | |
| Recruiting |
NCT06431854 -
Evaluation of a New Treatment Program for Adolescents With Eating Disorders: MINERVA Program
|
N/A | |
| Recruiting |
NCT02960152 -
Periodontal Impact of Eating Disorders (the PERIOED Study)
|
N/A | |
| Completed |
NCT00916071 -
Association Between Attention Deficit Hyperactivity Disorder and Bulimia Nervosa in Outpatients With Eating Disorders
|
N/A | |
| Terminated |
NCT00308776 -
Cholecystokinin for Reducing Binge Eating in People With Bulimia Nervosa
|
N/A |