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Bruxism clinical trials

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NCT ID: NCT06457646 Not yet recruiting - Bruxism Clinical Trials

mRNA Expression and Genetic Polymorphisms Affecting DRD3 (rs6280) and HTR2A (rs6313) in Bruxism

Start date: June 2, 2024
Phase:
Study type: Observational

The goal of this observational study is to learn about the genetic factors influencing bruxism, a condition characterized by teeth grinding, in a group of participants. The main questions it aims to answer are: - Is there a significant association between the rs6313 polymorphism of the HTR2A gene and bruxism? - Is there a significant association between the rs6280 polymorphism of the DRD3 gene and bruxism? Participants will: Provide DNA samples for genotyping of the DRD3 (rs6280) and HTR2A (rs6313) polymorphisms. Provide RNA samples to assess changes in the expression of HTR2A and DRD3. Researchers will compare the genetic data and RNA expression levels between individuals with bruxism and those without (controls) to see if there are significant genetic differences and expression changes associated with bruxism.

NCT ID: NCT06435208 Not yet recruiting - Periodontitis Clinical Trials

Impact of Subgingival Instrumentation on Psychological Distress and Mental Health Status in Bruxers With Periodontitis

Start date: June 1, 2024
Phase: N/A
Study type: Interventional

Bruxism is a non-functional repetitive jaw-muscle activity characterized by grinding or clenching the teeth. Bruxism, characterized by the involuntary grinding or clenching of teeth, is a prevalent parafunctional habit affecting individuals of all ages. Stress, anxiety, and depression are the psychological factors most commonly associated with the presence of bruxism.

NCT ID: NCT06429917 Not yet recruiting - Periodontitis Clinical Trials

Impact of Subgingival Instrumentation on Jaw Symptoms of Probable Bruxers Among Patients With Periodontitis

Start date: August 2024
Phase: N/A
Study type: Interventional

This study aims to explore the mechanisms by which periodontal disease affects the bruxers and to assess the impact of subgingival instrumentation on jaw symptoms of probable bruxers among patients with periodontitis .

NCT ID: NCT06386809 Not yet recruiting - Bruxism Clinical Trials

Effectiveness of Transcutaneous Auricular Vagus Nerve Stimulation in Bruxism

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

Our study aimed to investigate the effects of transcutaneous auricular vagus nerve stimulation (TAVNS) application on treatment efficacy in bruxism in terms of masseter muscle activity, pain, stress level, sleep and life quality, and autonomic functions.

NCT ID: NCT06088238 Not yet recruiting - Bruxism Clinical Trials

Endocrine Disruptors in Saliva Released From Bruxism Splints.

Start date: June 20, 2024
Phase:
Study type: Observational [Patient Registry]

The effects of endocrine disruptors (EDs) are well known. Therefore, the aim of this observational study is to analyse saliva samples from volunteers who request a bruxism splint, before, during and after fitting, to find out whether they are assimilated by the body, answering the following questions: - Do Michigan-type splints release endocrine disruptors or substances of particular concern? - In what concentration are they present in saliva? Participants will be asked to take saliva samples at different times over a period of 6 months. This will also be accompanied by the relevant clinical and oral history. A previous in vitro study is required, which is complemented by an in vivo study. The methodology is new in dentistry: super solvents which, combined with liquid chromatography coupled to a mass spectrometer (LC-HRMS), allows a wider range of substances to be detected, in a more ecological and simpler way, as they are not organic solvents derived from petroleum. The splint is chosen because it is an everyday treatment, which is increasingly in demand, especially after the pandemic. It is subdivided into two types, depending on the method of manufacture: injected and printed (more ecofriendly).

NCT ID: NCT06052709 Not yet recruiting - Bruxism Clinical Trials

Investigation of Occupational Balance in Individuals With and Without Bruxism

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

Considering that occupational balance and bruxism are negatively affected by stress, this study aims to determine whether there is a difference in terms of occupational balance between individuals with and without bruxism.

NCT ID: NCT05980559 Not yet recruiting - Bruxism Clinical Trials

Evaluation of BTX Injections in Treatment of Bruxism

Start date: January 15, 2024
Phase: Phase 3
Study type: Interventional

Aim of this study is to evaluate the effect of botulinum toxin type A (Xeomin®) on patients complaining from bruxism. The study will be a one arm clinical trial. Twelve subjects reporting bruxism irresponsive to conventional treatment modalities will be recruited and will be injected with botulinum toxin A (Xeomin®) in both masseter and temporalis muscles. Pain levels, Electromyographic activity and maximum occlusal force will be recorded in the subjects before injection and at 1 and 3 months after injection to determine the effect of treatment

NCT ID: NCT05784454 Not yet recruiting - Sleep Bruxism Clinical Trials

Prevalance of Sleep Bruxism Among a Group of Egyptian Children

Start date: May 2, 2023
Phase:
Study type: Observational

The goal of this observational study is to detect the prevalence of sleep bruxism in a group of Egyptian children and detect its relation to screen-time and sugar consumption. The main questions it aims to answer are: 1. In a group of Egyptian Children what is the prevalence of sleep bruxism? 2. What is the relation between sleep bruxism and screen time and sugar consumption?

NCT ID: NCT05769166 Not yet recruiting - Bruxism Clinical Trials

Prevalence Of Deleterious Oral Habits Among a Group of School Children in Cairo, Egypt: Cross-Sectional Study

ACU333
Start date: April 1, 2023
Phase:
Study type: Observational

This study aims to detect the prevalence of practicing oral habits among a group of school children in Cairo, Egypt.

NCT ID: NCT05764694 Not yet recruiting - Bruxism Clinical Trials

Correlation Between the Occurrence of School Bullying, Victimization, and the Occurrence of Deleterious Oral Habits.

Start date: September 1, 2023
Phase:
Study type: Observational

To determine the correlation between the occurrence of bullying, victimization, and deleterious oral habit in a group of Egyptian school children.